Therapeutic vascular systems

H. G. Clark; C. M. Agrawal; R. S. Stack

Therapeutic vascular systems

H. G. Clark, C. M. Agrawal, R. S. Stack

Medicine

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

The research program of Unit 1.2A, Therapeutic Vascular Systems, of the National Science Foundation/Engineering Research Center (NSF/ERC) is described. The unit's goal is to develop polymeric stents (stiffening elements) that can be implanted in a diseased artery simultaneously or sequentially to percutaneous transluminal coronary angioplasty (PTCA), and to make these stents in such a way that they will become encapsulated by tissue, degraded, and eventually absorbed. The unit produced stents from nylon, polyglycolic acid, and poly(L-lactic acid) and developed a method for in vitro evaluation of mechanical properties. A poly(L-lactic acid) stent has been placed in the femoral artery of a dog, and the vessel has remained patent for several months. In vitro testing of Vicryl (lactic/glycolic acid copolymer) stents show that they rapidly lose modulus due to plasticization by warm water, and nylon was also unsatisfactory, although better than Vicryl.

Original language	English (US)
Title of host publication	Biomedical Engineering Perspectives
Subtitle of host publication	Health Care Technologies for the 1990's and Beyond
Publisher	Publ by IEEE
Pages	671-672
Number of pages	2
Edition	pt 2
ISBN (Print)	0879425598
State	Published - Dec 1 1990
Event	Proceedings of the 12th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Philadelphia, PA, USA Duration: Nov 1 1990 → Nov 4 1990

Publication series

Name	Proceedings of the Annual Conference on Engineering in Medicine and Biology
Number	pt 2
ISSN (Print)	0589-1019

Other

Other	Proceedings of the 12th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
City	Philadelphia, PA, USA
Period	11/1/90 → 11/4/90

ASJC Scopus subject areas

Signal Processing
Biomedical Engineering
Computer Vision and Pattern Recognition
Health Informatics

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Cite this

Therapeutic vascular systems. / Clark, H. G.; Agrawal, C. M.; Stack, R. S.

Biomedical Engineering Perspectives: Health Care Technologies for the 1990's and Beyond. pt 2. ed. Publ by IEEE, 1990. p. 671-672 (Proceedings of the Annual Conference on Engineering in Medicine and Biology; No. pt 2).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Clark, HG, Agrawal, CM & Stack, RS 1990, Therapeutic vascular systems. in Biomedical Engineering Perspectives: Health Care Technologies for the 1990's and Beyond. pt 2 edn, Proceedings of the Annual Conference on Engineering in Medicine and Biology, no. pt 2, Publ by IEEE, pp. 671-672, Proceedings of the 12th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Philadelphia, PA, USA, 11/1/90.

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