Therapeutic strategies in autoimmune disease: Cyclosporin A as a model agent

D. E. Lemley, P. Katz

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Cyclosporin A is the derivative of the cyclic undecapeptide which is produced by 2 strains of fungi, Cylindrocapon lucidum Booth and Tolypocladium inflatum Gams. The drug has achieved widespread use in the treatment of organ transplant recipients as a vanguard against rejection, and currently is being evaluated as an immunosuppressive agent for the therapy of primary autoimmune phenomena as well. Its mechanism of action, and application to the treatment of rheumatologic disorders will be discussed.

Original languageEnglish
Pages (from-to)115-118
Number of pages4
JournalIn Vivo
Volume2
Issue number1
StatePublished - Jan 1 1988
Externally publishedYes

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Transplants
Immunosuppressive Agents
Fungi
Cyclosporine
Autoimmune Diseases
Derivatives
Pharmaceutical Preparations
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Therapeutic strategies in autoimmune disease : Cyclosporin A as a model agent. / Lemley, D. E.; Katz, P.

In: In Vivo, Vol. 2, No. 1, 01.01.1988, p. 115-118.

Research output: Contribution to journalArticle

Lemley, DE & Katz, P 1988, 'Therapeutic strategies in autoimmune disease: Cyclosporin A as a model agent', In Vivo, vol. 2, no. 1, pp. 115-118.
Lemley, D. E. ; Katz, P. / Therapeutic strategies in autoimmune disease : Cyclosporin A as a model agent. In: In Vivo. 1988 ; Vol. 2, No. 1. pp. 115-118.
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