Therapeutic implications of the natural history of advanced cervical cancer as defined by pretreatment surgical staging

Roger A. Potish, Leo B. Twiggs, Takashi Okagaki, Konald A. Prem, Leon L. Adcock

Research output: Contribution to journalArticle

39 Scopus citations

Abstract

From 1978 to 1983, 112 women with advanced cervical carcinomas received radiotherapy after pretreatment surgical staging. Five-year actuarial relapse-free survival rates were a strong function of lymphatic spread: 40% with periaortic node metastases, 50% with pelvic node metastases, and 84% without node metastases. Primary treatment failure had a distant component in 75% of recurrences (50% of recurrences with negative nodes and 85% of recurrences with positive nodes). It was concluded that adjuvant systemic therapy is necessary to substantially raise the probability of cure.

Original languageEnglish (US)
Pages (from-to)956-960
Number of pages5
JournalCancer
Volume56
Issue number4
DOIs
StatePublished - Aug 15 1985

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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