Therapeutic Cloning and Tissue Engineering

Chester J. Koh, Anthony Atala

Research output: Chapter in Book/Report/Conference proceedingChapter

20 Scopus citations

Abstract

A severe shortage of donor organs available for transplantation in the United States leaves patients suffering from diseased and injured organs with few treatment options. Scientists in the field of tissue engineering apply the principles of cell transplantation, material science, and engineering to construct biological substitutes that will restore and maintain normal function in diseased and injured tissues. Therapeutic cloning, where the nucleus from a donor cell is transferred into an enucleated oocyte in order to extract pluripotent embryonic stem cells, offers a potentially limitless source of cells for tissue engineering applications. The present chapter reviews recent advances that have occurred in therapeutic cloning and tissue engineering and describes applications of these new technologies that may offer novel therapies for patients with end-stage organ failure.

Original languageEnglish (US)
Title of host publicationCurrent Topics in Developmental Biology
Pages1-15
Number of pages15
DOIs
StatePublished - Dec 1 2004

Publication series

NameCurrent Topics in Developmental Biology
Volume60
ISSN (Print)0070-2153

ASJC Scopus subject areas

  • Developmental Biology
  • Cell Biology

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  • Cite this

    Koh, C. J., & Atala, A. (2004). Therapeutic Cloning and Tissue Engineering. In Current Topics in Developmental Biology (pp. 1-15). (Current Topics in Developmental Biology; Vol. 60). https://doi.org/10.1016/S0070-2153(04)60001-9