Theoretical basis for measurements of cartilage fixed-charge density using streaming current and electro-osmosis effects

W. Y. Gu, W. M. Lai, V. C. Mow

Research output: Chapter in Book/Report/Conference proceedingConference contribution

8 Scopus citations

Abstract

Fluid flow and ion transport effects under an applied pressure with a streaming current, or under an applied electric potential were analyzed using the triphasic theory. The results showed that charged hydrated soft issues such as articular cartilage would appear more permeable when tested in the presence of a streaming current than when tested in the presence of a streaming potential. This is because the streaming potential is always against the ion transport convected by the fluid. The permeability determined under the streaming current condition (i.e. the hydraulic permeability) is almost independent of the fixed-charge density(FCD) of the tissue. Stress and strain fields within the specimen, under the electroosmotic conditions, were also calculated. Based on these calculations estimates were provided to assess the possible errors inherent in measuring tissue FCD from these types of electro-kinetic experiments.

Original languageEnglish (US)
Title of host publicationAdvances in Bioengineering
EditorsJohn M. Tarbell
PublisherPubl by ASME
Pages55-58
Number of pages4
ISBN (Print)0791810313
StatePublished - Dec 1 1993
Externally publishedYes
EventProceedings of the 1993 ASME Winter Annual Meeting - New Orleans, LA, USA
Duration: Nov 28 1993Dec 3 1993

Publication series

NameAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
Volume26

Other

OtherProceedings of the 1993 ASME Winter Annual Meeting
CityNew Orleans, LA, USA
Period11/28/9312/3/93

ASJC Scopus subject areas

  • Engineering(all)

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  • Cite this

    Gu, W. Y., Lai, W. M., & Mow, V. C. (1993). Theoretical basis for measurements of cartilage fixed-charge density using streaming current and electro-osmosis effects. In J. M. Tarbell (Ed.), Advances in Bioengineering (pp. 55-58). (American Society of Mechanical Engineers, Bioengineering Division (Publication) BED; Vol. 26). Publ by ASME.