The value of the autopsy in congenital heart disease

M. H. Kay, D. S. Moodie, R. Sterba, D. J. Murphy, Eliot Rosenkranz, N. Ratliff, A. Homa

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

We reviewed autopsies in 50 consecutive cases of congenital heart disease between 1980 and 1988. Autopsy results were compared to premortem clinical diagnosis. The patients ranged in age from two days to 66.5 years with a mean age of 6.42 years; 68% were less than one year of age. The most common diagnoses were hypoplastic left heart syndrome in 16 (32%) and ventricular septal defect in five (10%). Other common diagnoses included coarctation of the aorta, hypoplastic right heart syndrome, tetralogy of Fallot, transposition of the great vessels and tricuspid atresia. No patient had a missed diagnosis that would have changed survival (Class 1). Four (8%) of the patients had one missed major diagnosis that did not change their survival because they were already being symptomatically treated or because no clinical treatment was available (Class 2). The majority of autopsy derived data were missed minor diagnoses that were related [14(28%)-Class 3] or unrelated [12(24%) - Class 4] to the terminal disease process. However, despite the small percentage of autopsy findings that would have directly affected survival, the autopsy provided important additional clinical information in 30 (60%) patients. This information could be used to correct management errors and to develop protocols for prophylaxis against known complications. The pediatric autopsy can provide useful clinical data that may be a guide to altering clinical therapy and is essential in providing genetic counseling.

Original languageEnglish
Pages (from-to)450-454
Number of pages5
JournalClinical Pediatrics
Volume30
Issue number7
StatePublished - Jan 1 1991
Externally publishedYes

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Autopsy
Heart Diseases
Survival
Tricuspid Atresia
Hypoplastic Left Heart Syndrome
Transposition of Great Vessels
Aortic Coarctation
Tetralogy of Fallot
Ventricular Heart Septal Defects
Genetic Counseling
Pediatrics
Therapeutics

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Kay, M. H., Moodie, D. S., Sterba, R., Murphy, D. J., Rosenkranz, E., Ratliff, N., & Homa, A. (1991). The value of the autopsy in congenital heart disease. Clinical Pediatrics, 30(7), 450-454.

The value of the autopsy in congenital heart disease. / Kay, M. H.; Moodie, D. S.; Sterba, R.; Murphy, D. J.; Rosenkranz, Eliot; Ratliff, N.; Homa, A.

In: Clinical Pediatrics, Vol. 30, No. 7, 01.01.1991, p. 450-454.

Research output: Contribution to journalArticle

Kay, MH, Moodie, DS, Sterba, R, Murphy, DJ, Rosenkranz, E, Ratliff, N & Homa, A 1991, 'The value of the autopsy in congenital heart disease', Clinical Pediatrics, vol. 30, no. 7, pp. 450-454.
Kay MH, Moodie DS, Sterba R, Murphy DJ, Rosenkranz E, Ratliff N et al. The value of the autopsy in congenital heart disease. Clinical Pediatrics. 1991 Jan 1;30(7):450-454.
Kay, M. H. ; Moodie, D. S. ; Sterba, R. ; Murphy, D. J. ; Rosenkranz, Eliot ; Ratliff, N. ; Homa, A. / The value of the autopsy in congenital heart disease. In: Clinical Pediatrics. 1991 ; Vol. 30, No. 7. pp. 450-454.
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