The Transradial Approach to Percutaneous Coronary Intervention. Historical Perspective, Current Concepts, and Future Directions

Sunil V. Rao, Mauricio G Cohen, David E. Kandzari, Olivier F. Bertrand, Ian C. Gilchrist

Research output: Contribution to journalArticle

226 Citations (Scopus)

Abstract

Periprocedural bleeding complications after percutaneous coronary intervention (PCI) are associated with increased short- and long-term morbidity and mortality. Although clinical trials have primarily assessed pharmacological strategies for reducing bleeding risk, there is a mounting body of evidence suggesting that adoption of a transradial rather than a transfemoral approach to PCI may permit greater reductions in bleeding risk than have been achieved with pharmacological strategies alone. However, despite a long history of use, a lack of widespread uptake by physicians coupled with the technological limitations of available devices has in the past confined transradial PCI to the status of a niche procedure, and many operators lack experience in this technique. In this review, we examine the history of the transradial approach to PCI and discuss some of the circumstances that have hitherto limited its appeal. We then review the current state of the peer-reviewed literature supporting its use and summarize the unresolved issues affecting broader application of this technique, including lack of operator familiarity and an insufficient evidence base for guiding practice. Finally, we describe potential directions for future investigation in the transradial realm.

Original languageEnglish
Pages (from-to)2187-2195
Number of pages9
JournalJournal of the American College of Cardiology
Volume55
Issue number20
DOIs
StatePublished - May 18 2010

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Percutaneous Coronary Intervention
Hemorrhage
Pharmacology
History
Clinical Trials
Morbidity
Physicians
Equipment and Supplies
Mortality
Direction compound

Keywords

  • acute coronary syndromes
  • percutaneous coronary intervention
  • review
  • transradial

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

The Transradial Approach to Percutaneous Coronary Intervention. Historical Perspective, Current Concepts, and Future Directions. / Rao, Sunil V.; Cohen, Mauricio G; Kandzari, David E.; Bertrand, Olivier F.; Gilchrist, Ian C.

In: Journal of the American College of Cardiology, Vol. 55, No. 20, 18.05.2010, p. 2187-2195.

Research output: Contribution to journalArticle

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