The Tear Film: Pathological Conditions

Vikram Paranjpe, Anat Galor

Research output: Chapter in Book/Report/Conference proceedingChapter


This chapter first reviews the pathogenesis of dry eye (DE) and the pathological effects DE has on the properties and composition of the tear film, lacrimal and meibomian glands, and goblet cells. Next, the pathologic changes that occur with two DE related risk factors: aging and the use of glaucoma eye drops are discussed. Finally, the clinical consequences of tear film, lacrimal gland, meibomian gland, and goblet cell alterations, focusing on visual function, nerve modulation, quality of life, and economic burden, are explored.

Original languageEnglish (US)
Title of host publicationModeling and Simulation in Science, Engineering and Technology
Number of pages25
StatePublished - 2019

Publication series

NameModeling and Simulation in Science, Engineering and Technology
ISSN (Print)2164-3679
ISSN (Electronic)2164-3725


  • Aging
  • Dry eye
  • Glaucoma medication
  • Nerve modulation
  • Quality of life
  • Visual function

ASJC Scopus subject areas

  • Modeling and Simulation
  • Engineering(all)
  • Fluid Flow and Transfer Processes
  • Computational Mathematics


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