The status of the corticotropin releasing factor (CRF)

Murray Saffran; A. V. Schally

doi:10.1159/000122723

The status of the corticotropin releasing factor (CRF)

Murray Saffran, A. V. Schally

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

Early in the history of studies on the release of ACTH by stress there were indications that ACTH might be released by multiple factors. But the neurohumoral theory, as formulated by G.W. Harris, suggested that every hypophysial hormone had its unique hypothalamic controlling agent and a search for the unique ACTH-releasing hormone went on for about 20 years. This review reexamines the case for multiple releasers of ACTH.

Original language	English (US)
Pages (from-to)	359-375
Number of pages	17
Journal	Neuroendocrinology
Volume	24
Issue number	5-6
DOIs	https://doi.org/10.1159/000122723
State	Published - 1977
Externally published	Yes

Keywords

ACTH-Release
Adrenal cortex
Anterior pituitary
CRF
Hypothalamus
Stress
Vasopressin

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology
Endocrine and Autonomic Systems
Cellular and Molecular Neuroscience

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1159/000122723

Cite this

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abstract = "Early in the history of studies on the release of ACTH by stress there were indications that ACTH might be released by multiple factors. But the neurohumoral theory, as formulated by G.W. Harris, suggested that every hypophysial hormone had its unique hypothalamic controlling agent and a search for the unique ACTH-releasing hormone went on for about 20 years. This review reexamines the case for multiple releasers of ACTH.",

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AU - Schally, A. V.

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AB - Early in the history of studies on the release of ACTH by stress there were indications that ACTH might be released by multiple factors. But the neurohumoral theory, as formulated by G.W. Harris, suggested that every hypophysial hormone had its unique hypothalamic controlling agent and a search for the unique ACTH-releasing hormone went on for about 20 years. This review reexamines the case for multiple releasers of ACTH.

KW - ACTH-Release

KW - Adrenal cortex

KW - Anterior pituitary

KW - CRF

KW - Hypothalamus

KW - Stress

KW - Vasopressin

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SN - 0028-3835

IS - 5-6

ER -

The status of the corticotropin releasing factor (CRF)

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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