The spectrum of bleeding in women and girls with haemophilia B

J. Staber, S. E. Croteau, Joanna A Davis, E. F. Grabowski, P. Kouides, R. F. Sidonio

Research output: Contribution to journalArticle

Abstract

Although hemophilia B affects 1 in 25,000 males there may be 3 female hemophilia B carriers per affected male. This clinical review highlights the unique challenges faced by hemophilia B carriers including the under-recognition of bleeding symptoms associated with and without FIX deficiency, discrepancies in correlation between genotype and bleeding phenotype and therapeutic considerations utilizing clinical vignettes of common scenarios.

Original languageEnglish (US)
JournalHaemophilia
DOIs
StateAccepted/In press - Jan 1 2017

Fingerprint

Hemophilia B
Hemorrhage
Genotype
Phenotype
Therapeutics

Keywords

  • Haemophilia
  • Haemophilia carriers
  • Review
  • Women with bleeding disorders

ASJC Scopus subject areas

  • Hematology
  • Genetics(clinical)

Cite this

Staber, J., Croteau, S. E., Davis, J. A., Grabowski, E. F., Kouides, P., & Sidonio, R. F. (Accepted/In press). The spectrum of bleeding in women and girls with haemophilia B. Haemophilia. https://doi.org/10.1111/hae.13376

The spectrum of bleeding in women and girls with haemophilia B. / Staber, J.; Croteau, S. E.; Davis, Joanna A; Grabowski, E. F.; Kouides, P.; Sidonio, R. F.

In: Haemophilia, 01.01.2017.

Research output: Contribution to journalArticle

Staber, J, Croteau, SE, Davis, JA, Grabowski, EF, Kouides, P & Sidonio, RF 2017, 'The spectrum of bleeding in women and girls with haemophilia B', Haemophilia. https://doi.org/10.1111/hae.13376
Staber J, Croteau SE, Davis JA, Grabowski EF, Kouides P, Sidonio RF. The spectrum of bleeding in women and girls with haemophilia B. Haemophilia. 2017 Jan 1. https://doi.org/10.1111/hae.13376
Staber, J. ; Croteau, S. E. ; Davis, Joanna A ; Grabowski, E. F. ; Kouides, P. ; Sidonio, R. F. / The spectrum of bleeding in women and girls with haemophilia B. In: Haemophilia. 2017.
@article{ebce7356404a4de58f3a9841cd2a8dd8,
title = "The spectrum of bleeding in women and girls with haemophilia B",
abstract = "Although hemophilia B affects 1 in 25,000 males there may be 3 female hemophilia B carriers per affected male. This clinical review highlights the unique challenges faced by hemophilia B carriers including the under-recognition of bleeding symptoms associated with and without FIX deficiency, discrepancies in correlation between genotype and bleeding phenotype and therapeutic considerations utilizing clinical vignettes of common scenarios.",
keywords = "Haemophilia, Haemophilia carriers, Review, Women with bleeding disorders",
author = "J. Staber and Croteau, {S. E.} and Davis, {Joanna A} and Grabowski, {E. F.} and P. Kouides and Sidonio, {R. F.}",
year = "2017",
month = "1",
day = "1",
doi = "10.1111/hae.13376",
language = "English (US)",
journal = "Haemophilia",
issn = "1351-8216",
publisher = "Wiley-Blackwell",

}

TY - JOUR

T1 - The spectrum of bleeding in women and girls with haemophilia B

AU - Staber, J.

AU - Croteau, S. E.

AU - Davis, Joanna A

AU - Grabowski, E. F.

AU - Kouides, P.

AU - Sidonio, R. F.

PY - 2017/1/1

Y1 - 2017/1/1

N2 - Although hemophilia B affects 1 in 25,000 males there may be 3 female hemophilia B carriers per affected male. This clinical review highlights the unique challenges faced by hemophilia B carriers including the under-recognition of bleeding symptoms associated with and without FIX deficiency, discrepancies in correlation between genotype and bleeding phenotype and therapeutic considerations utilizing clinical vignettes of common scenarios.

AB - Although hemophilia B affects 1 in 25,000 males there may be 3 female hemophilia B carriers per affected male. This clinical review highlights the unique challenges faced by hemophilia B carriers including the under-recognition of bleeding symptoms associated with and without FIX deficiency, discrepancies in correlation between genotype and bleeding phenotype and therapeutic considerations utilizing clinical vignettes of common scenarios.

KW - Haemophilia

KW - Haemophilia carriers

KW - Review

KW - Women with bleeding disorders

UR - http://www.scopus.com/inward/record.url?scp=85035211300&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85035211300&partnerID=8YFLogxK

U2 - 10.1111/hae.13376

DO - 10.1111/hae.13376

M3 - Article

JO - Haemophilia

JF - Haemophilia

SN - 1351-8216

ER -