The severity and role of somatic depressive symptoms in psychological networks in a longitudinal sample of peripartum women

Lara Michelle Baez, D. Jeffrey Newport, Zachary N. Stowe, Bettina T. Knight, Aaron Shain Heller

Research output: Contribution to journalArticlepeer-review


The inclusion of somatic symptoms in assessing peripartum depression (PPD), which encompasses depression during pregnancy and the postpartum period, has remained controversial, as there is substantial overlap between somatic depression symptoms and normal features of pregnancy/postpartum. This study examined whether trajectories differed by PPD symptom subscale and whether PPD symptom networks changed as a function of the peripartum phase. 418 women with a history of neuropsychiatric illness participated in a longitudinal observational study, completing symptom questionnaires assessing affective, cognitive, and somatic symptoms throughout pregnancy and the first year postpartum. Assessments were grouped into five peripartum phases: three trimesters of pregnancy and early/late postpartum. Two analyses were performed. First, a series of multilevel spline regression models examined depression subscale trajectories over peripartum phase. Second, symptom networks and related metrics were estimated for each peripartum phase and compared. Somatic symptoms were most severe and had the most variable peripartum trajectory. The role of somatic symptoms within the networks also changed as a function of peripartum phase. Our results suggest that somatic symptoms can be severe and may play a crucial role in the maintenance of PPD. Thus, somatic symptoms should not be disregarded when assessing for PPD in obstetrical, psychiatric, and pediatric clinics, and clinical research.

Original languageEnglish (US)
Pages (from-to)283-289
Number of pages7
JournalJournal of Psychiatric Research
StatePublished - Oct 2021
Externally publishedYes


  • Multilevel modeling
  • Network analysis
  • Postpartum
  • Postpartum depression
  • Pregnancy
  • Somatic symptoms

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry


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