The Search for Neuroprotective Strategies in Stroke

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

Neuroprotection is a worthwhile pursuit given the tremendous costs posed on society by neurologic disease. Numerous difficulties in translating experimental data to clinical use have plagued the field, as demonstrated by the list of therapies discarded from clinical trials. Physicians and scientists from around the world have reevaluated past problems and are looking forward to improvements in clinical investigations. Combining thrombolytics with neuroprotective strategies, including antiexcitotoxic agents, free radical scavengers, vascular protective agents, antiinflammatories, and hypothermia, shows great promise and a bright future for treating cerebrovascular disease.

Original languageEnglish
Pages (from-to)181-194
Number of pages14
JournalAmerican Journal of Neuroradiology
Volume25
Issue number2
StatePublished - Feb 1 2004

Fingerprint

Cerebrovascular Disorders
Protective Agents
Free Radical Scavengers
Nervous System Diseases
Hypothermia
Blood Vessels
Anti-Inflammatory Agents
Stroke
Clinical Trials
Physicians
Costs and Cost Analysis
Therapeutics
Neuroprotection

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

The Search for Neuroprotective Strategies in Stroke. / Danton, Gary; Dalton Dietrich, W.

In: American Journal of Neuroradiology, Vol. 25, No. 2, 01.02.2004, p. 181-194.

Research output: Contribution to journalArticle

@article{16d9d08d7f834150879bdfe6fce764cc,
title = "The Search for Neuroprotective Strategies in Stroke",
abstract = "Neuroprotection is a worthwhile pursuit given the tremendous costs posed on society by neurologic disease. Numerous difficulties in translating experimental data to clinical use have plagued the field, as demonstrated by the list of therapies discarded from clinical trials. Physicians and scientists from around the world have reevaluated past problems and are looking forward to improvements in clinical investigations. Combining thrombolytics with neuroprotective strategies, including antiexcitotoxic agents, free radical scavengers, vascular protective agents, antiinflammatories, and hypothermia, shows great promise and a bright future for treating cerebrovascular disease.",
author = "Gary Danton and {Dalton Dietrich}, W.",
year = "2004",
month = "2",
day = "1",
language = "English",
volume = "25",
pages = "181--194",
journal = "American Journal of Neuroradiology",
issn = "0195-6108",
publisher = "American Society of Neuroradiology",
number = "2",

}

TY - JOUR

T1 - The Search for Neuroprotective Strategies in Stroke

AU - Danton, Gary

AU - Dalton Dietrich, W.

PY - 2004/2/1

Y1 - 2004/2/1

N2 - Neuroprotection is a worthwhile pursuit given the tremendous costs posed on society by neurologic disease. Numerous difficulties in translating experimental data to clinical use have plagued the field, as demonstrated by the list of therapies discarded from clinical trials. Physicians and scientists from around the world have reevaluated past problems and are looking forward to improvements in clinical investigations. Combining thrombolytics with neuroprotective strategies, including antiexcitotoxic agents, free radical scavengers, vascular protective agents, antiinflammatories, and hypothermia, shows great promise and a bright future for treating cerebrovascular disease.

AB - Neuroprotection is a worthwhile pursuit given the tremendous costs posed on society by neurologic disease. Numerous difficulties in translating experimental data to clinical use have plagued the field, as demonstrated by the list of therapies discarded from clinical trials. Physicians and scientists from around the world have reevaluated past problems and are looking forward to improvements in clinical investigations. Combining thrombolytics with neuroprotective strategies, including antiexcitotoxic agents, free radical scavengers, vascular protective agents, antiinflammatories, and hypothermia, shows great promise and a bright future for treating cerebrovascular disease.

UR - http://www.scopus.com/inward/record.url?scp=1242339543&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=1242339543&partnerID=8YFLogxK

M3 - Article

C2 - 14970016

AN - SCOPUS:1242339543

VL - 25

SP - 181

EP - 194

JO - American Journal of Neuroradiology

JF - American Journal of Neuroradiology

SN - 0195-6108

IS - 2

ER -