The Search for Neuroprotective Strategies in Stroke

Research output: Contribution to journalReview articlepeer-review

49 Scopus citations


Neuroprotection is a worthwhile pursuit given the tremendous costs posed on society by neurologic disease. Numerous difficulties in translating experimental data to clinical use have plagued the field, as demonstrated by the list of therapies discarded from clinical trials. Physicians and scientists from around the world have reevaluated past problems and are looking forward to improvements in clinical investigations. Combining thrombolytics with neuroprotective strategies, including antiexcitotoxic agents, free radical scavengers, vascular protective agents, antiinflammatories, and hypothermia, shows great promise and a bright future for treating cerebrovascular disease.

Original languageEnglish (US)
Pages (from-to)181-194
Number of pages14
JournalAmerican Journal of Neuroradiology
Issue number2
StatePublished - Feb 2004

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology


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