The safety and efficacy of naftifine cream 1% in the treatment of tinea pedis

L. A. Schachner, F. K. Bagatell, C. V. Whittington, I. Willis, J. Sefton, R. E. DeGryse

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Naftifine cream 1% was compared with its vehicle during a 6-week, double-blind, randomized, parallel-group study of 91 subjects with tinea pedis. After 4 weeks of twice-daily treatment, 57% of the subjects treated with naftifine and 38% of those treated with its vehicle had negative microscopic findings and negative fungal cultures (p=0.038). Two weeks after the conclusion of treatment (week 6), 62% of the naftifine group and 29% of the vehicle group had negative mycological findings (p=0.002). Naftfine was significantly more effective than its vehicle in reducing fungal scaling and fissuring (p<0.04). It was concluded that naftifine cream 1% is safe and significantly more effective than its vehicle in treating tinea pedis.

Original languageEnglish (US)
Pages (from-to)148-152
Number of pages5
JournalAdvances in Therapy
Volume7
Issue number3
StatePublished - Jan 1 1990
Externally publishedYes

ASJC Scopus subject areas

  • Pharmacology (medical)

Fingerprint Dive into the research topics of 'The safety and efficacy of naftifine cream 1% in the treatment of tinea pedis'. Together they form a unique fingerprint.

Cite this