Naftifine cream 1% was compared with its vehicle during a 6-week, double-blind, randomized, parallel-group study of 91 subjects with tinea pedis. After 4 weeks of twice-daily treatment, 57% of the subjects treated with naftifine and 38% of those treated with its vehicle had negative microscopic findings and negative fungal cultures (p=0.038). Two weeks after the conclusion of treatment (week 6), 62% of the naftifine group and 29% of the vehicle group had negative mycological findings (p=0.002). Naftfine was significantly more effective than its vehicle in reducing fungal scaling and fissuring (p<0.04). It was concluded that naftifine cream 1% is safe and significantly more effective than its vehicle in treating tinea pedis.
|Original language||English (US)|
|Number of pages||5|
|Journal||Advances in Therapy|
|State||Published - Jan 1 1990|
ASJC Scopus subject areas
- Pharmacology (medical)