The roles of glucose and AMP in regulating the conversion of phosphorylase a into phosphorylase b

J. Martyn Bailey, William J. Whelan

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

The ability of glucose to assist the action of phosphorylase a phosphatase on phosphorylase a, appears to be mediated through conformational changes in the phosphorylase. The system is an example of control of enzyme activity by regulation of the conformation of the substrate, and parallels the similar effect of AMP in inhibiting the dephosphorylation.

Original languageEnglish
Pages (from-to)191-197
Number of pages7
JournalBiochemical and Biophysical Research Communications
Volume46
Issue number1
DOIs
StatePublished - Jan 14 1972

Fingerprint

Phosphorylase b
Phosphorylase a
Adenosine Monophosphate
Phosphorylase Phosphatase
Glucose
Phosphorylases
Enzyme activity
Phosphoric Monoester Hydrolases
Conformations
Substrates
Enzymes

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

The roles of glucose and AMP in regulating the conversion of phosphorylase a into phosphorylase b. / Martyn Bailey, J.; Whelan, William J.

In: Biochemical and Biophysical Research Communications, Vol. 46, No. 1, 14.01.1972, p. 191-197.

Research output: Contribution to journalArticle

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