The roles of glucose and AMP in regulating the conversion of phosphorylase a into phosphorylase b

J. Martyn Bailey, W. J. Whelan

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33 Scopus citations


The ability of glucose to assist the action of phosphorylase a phosphatase on phosphorylase a, appears to be mediated through conformational changes in the phosphorylase. The system is an example of control of enzyme activity by regulation of the conformation of the substrate, and parallels the similar effect of AMP in inhibiting the dephosphorylation.

Original languageEnglish (US)
Pages (from-to)191-197
Number of pages7
JournalBiochemical and biophysical research communications
Issue number1
StatePublished - Jan 14 1972


ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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