TY - JOUR
T1 - The role of zinc in the treatment of acne
T2 - A review of the literature
AU - Cervantes, Jessica
AU - Eber, Ariel E.
AU - Perper, Marina
AU - Nascimento, Vanessa M.
AU - Nouri, Keyvan
AU - Keri, Jonette
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Acne vulgaris is a chronic disease of the pilosebaceous units presenting as inflammatory or noninflammatory lesions in individuals of all ages. The current standard of treatment includes topical formulations in the forms of washes, gels, lotions, and creams such as antibiotics, antibacterial agents, retinoids, and comedolytics. Additionally, systemic treatments are available for more severe or resistant forms of acne. Nevertheless, these treatments have shown to induce a wide array of adverse effects, including dryness, peeling, erythema, and even fetal defects and embolic events. Zinc is a promising alternative to other acne treatments owing to its low cost, efficacy, and lack of systemic side effects. In this literature review, we evaluate the effectiveness and side-effect profiles of various formulations of zinc used to treat acne.
AB - Acne vulgaris is a chronic disease of the pilosebaceous units presenting as inflammatory or noninflammatory lesions in individuals of all ages. The current standard of treatment includes topical formulations in the forms of washes, gels, lotions, and creams such as antibiotics, antibacterial agents, retinoids, and comedolytics. Additionally, systemic treatments are available for more severe or resistant forms of acne. Nevertheless, these treatments have shown to induce a wide array of adverse effects, including dryness, peeling, erythema, and even fetal defects and embolic events. Zinc is a promising alternative to other acne treatments owing to its low cost, efficacy, and lack of systemic side effects. In this literature review, we evaluate the effectiveness and side-effect profiles of various formulations of zinc used to treat acne.
KW - acne
KW - inflammatory disorders
KW - systemic therapy
KW - therapy topical
KW - zinc
UR - http://www.scopus.com/inward/record.url?scp=85041826099&partnerID=8YFLogxK
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U2 - 10.1111/dth.12576
DO - 10.1111/dth.12576
M3 - Review article
C2 - 29193602
AN - SCOPUS:85041826099
VL - 31
JO - Dermatologic Therapy
JF - Dermatologic Therapy
SN - 1396-0296
IS - 1
M1 - e12576
ER -