The role of transcranial Doppler in confirming brain death: Sensitivity, specificity, and suggestions for performance and interpretation

G. W. Petty, J. P. Mohr, T. A. Pedley, T. K. Tatemichi, L. Lennihan, D. I. Duterte, Ralph L Sacco

Research output: Contribution to journalArticle

134 Citations (Scopus)

Abstract

We performed transcranial Doppler (TCD) examinations on 54 comatose patients over a 1-year period. Of 49 patients with technically adequate TCD examinations, 23 met criteria for determination of brain death by clinical and EEG criteria (21) or clinical criteria alone (2; EEG not performed). A TCD waveform abnormality, consisting of absent or reversed diastolic flow, or small early systolic spikes, in at least 2 intracranial arteries, occurred in 21 brain-dead patients, but in none of the other patients in coma. With appropriate guidelines for performance and interpretation, TCD could be incorporated into institutional protocols as a rapid and convenient alternative to EEG for confirmation of brain death.

Original languageEnglish
Pages (from-to)300-303
Number of pages4
JournalNeurology
Volume40
Issue number2
StatePublished - Feb 1 1990
Externally publishedYes

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Brain Death
Sensitivity and Specificity
Electroencephalography
Coma
Arteries
Guidelines

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Petty, G. W., Mohr, J. P., Pedley, T. A., Tatemichi, T. K., Lennihan, L., Duterte, D. I., & Sacco, R. L. (1990). The role of transcranial Doppler in confirming brain death: Sensitivity, specificity, and suggestions for performance and interpretation. Neurology, 40(2), 300-303.

The role of transcranial Doppler in confirming brain death : Sensitivity, specificity, and suggestions for performance and interpretation. / Petty, G. W.; Mohr, J. P.; Pedley, T. A.; Tatemichi, T. K.; Lennihan, L.; Duterte, D. I.; Sacco, Ralph L.

In: Neurology, Vol. 40, No. 2, 01.02.1990, p. 300-303.

Research output: Contribution to journalArticle

Petty, GW, Mohr, JP, Pedley, TA, Tatemichi, TK, Lennihan, L, Duterte, DI & Sacco, RL 1990, 'The role of transcranial Doppler in confirming brain death: Sensitivity, specificity, and suggestions for performance and interpretation', Neurology, vol. 40, no. 2, pp. 300-303.
Petty GW, Mohr JP, Pedley TA, Tatemichi TK, Lennihan L, Duterte DI et al. The role of transcranial Doppler in confirming brain death: Sensitivity, specificity, and suggestions for performance and interpretation. Neurology. 1990 Feb 1;40(2):300-303.
Petty, G. W. ; Mohr, J. P. ; Pedley, T. A. ; Tatemichi, T. K. ; Lennihan, L. ; Duterte, D. I. ; Sacco, Ralph L. / The role of transcranial Doppler in confirming brain death : Sensitivity, specificity, and suggestions for performance and interpretation. In: Neurology. 1990 ; Vol. 40, No. 2. pp. 300-303.
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