The role of the vitreous in macular hole formation

Research output: Chapter in Book/Report/Conference proceedingChapter


Study of the pathogenesis of macular holes has been stimulated by the therapeutic opportunities that vitrectomy has offered. Initially thought to be due to anomalous separation of the vitreous from the central fovea, clinical observations and newer imaging modalities have demonstrated a more intricate and varied mechanism. Especially valuable has been the study of cases that appear to be precursor lesions by virtue of vitreofoveal attachments. Probably, there are several processes that jointly direct macular hole formation.

Original languageEnglish (US)
Title of host publicationEncyclopedia of the Eye, Four-Volume Set
Number of pages5
ISBN (Electronic)9780123742032
ISBN (Print)9780123741981
StatePublished - Jan 1 2010


  • Macular cysts
  • Macular hole
  • Retina
  • Traction
  • Trauma
  • Vitrectomy
  • Vitreous

ASJC Scopus subject areas

  • Medicine(all)


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