The role of neurotoxins in the periorbital and midfacial areas

Benjamin P. Erickson, Wendy Lee, Joel Cohen, Lisa Grunebaum

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


Initially popularized for the treatment of strabismus and blepharospasm, injection of botulinum neurotoxin has become the most commonly performed cosmetic treatment in the United States. Injection techniques have been particularly well-studied in the midface and periocular region, and patient satisfaction tends to be very high. We review the salient differences among available neurotoxins, how to optimally reconstitute them, how to inject the forehead, glabella, lateral canthal lines ("crow's feet"), infralid region, and transverse nasal lines ("bunny lines"), how to sculpt the brow, and how to manage potential complications.

Original languageEnglish (US)
Pages (from-to)243-255
Number of pages13
JournalFacial Plastic Surgery Clinics of North America
Issue number2
StatePublished - May 1 2015


  • AbobotulinumtoxinA
  • Botulinum toxin
  • Facial rhytids
  • IncobotulinumtoxinA
  • Neurotoxin
  • OnabotulinumtoxinA
  • RimabotulinumtoxinB

ASJC Scopus subject areas

  • Surgery


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