The role of intravitreal trimethoprim/sulfamethoxazole in the treatment of toxoplasma retinochoroiditis

Himadri Choudhury; Animesh Jindal; Avinash Pathengay; Abhishek Bawdekar; Thomas Albini; Harry W. Flynn

doi:10.3928/23258160-20150101-27

The role of intravitreal trimethoprim/sulfamethoxazole in the treatment of toxoplasma retinochoroiditis

Himadri Choudhury, Animesh Jindal, Avinash Pathengay, Abhishek Bawdekar, Thomas Albini, Harry W. Flynn

Ophthalmology

Research output: Contribution to journal › Review article › peer-review

13 Scopus citations

Abstract

The authors evaluate the role of intravitreal trimethoprim/sulfamethoxazole in the treatment of toxoplasma retinochoroiditis (TRC) in four patients. Intravitreal injection of trimethoprim/sulfamethoxazole 1.28 mg/0.08 mL with dexamethasone 400 ?g/0.1 mL was injected weekly or biweekly. After the initiation of treatment, a reduction in intraocular inflammation was observed clinically and on optical coherence tomography within 1 week. Three patients regained visual acuity of 20/20, and one patient improved to 20/40 with residual macular scarring. No evidence of retinal toxicity was noted on full-field electroretinogram. Intravitreal trimethoprim/sulfamethoxazole and dexamethasone combination may be an alternative treatment strategy in patients with TRC.

Original language	English (US)
Pages (from-to)	137-140
Number of pages	4
Journal	Ophthalmic Surgery Lasers and Imaging Retina
Volume	46
Issue number	1
DOIs	https://doi.org/10.3928/23258160-20150101-27
State	Published - Jan 1 2015

ASJC Scopus subject areas

Surgery
Ophthalmology

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The role of intravitreal trimethoprim/sulfamethoxazole in the treatment of toxoplasma retinochoroiditis. / Choudhury, Himadri; Jindal, Animesh; Pathengay, Avinash; Bawdekar, Abhishek; Albini, Thomas ; Flynn, Harry W.

In: Ophthalmic Surgery Lasers and Imaging Retina, Vol. 46, No. 1, 01.01.2015, p. 137-140.

Research output: Contribution to journal › Review article › peer-review

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The role of intravitreal trimethoprim/sulfamethoxazole in the treatment of toxoplasma retinochoroiditis

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