The role of intravitreal trimethoprim/sulfamethoxazole in the treatment of toxoplasma retinochoroiditis

Himadri Choudhury, Animesh Jindal, Avinash Pathengay, Abhishek Bawdekar, Thomas A Albini, Harry W Flynn

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The authors evaluate the role of intravitreal trimethoprim/sulfamethoxazole in the treatment of toxoplasma retinochoroiditis (TRC) in four patients. Intravitreal injection of trimethoprim/sulfamethoxazole 1.28 mg/0.08 mL with dexamethasone 400 ?g/0.1 mL was injected weekly or biweekly. After the initiation of treatment, a reduction in intraocular inflammation was observed clinically and on optical coherence tomography within 1 week. Three patients regained visual acuity of 20/20, and one patient improved to 20/40 with residual macular scarring. No evidence of retinal toxicity was noted on full-field electroretinogram. Intravitreal trimethoprim/sulfamethoxazole and dexamethasone combination may be an alternative treatment strategy in patients with TRC.

Original languageEnglish
Pages (from-to)137-140
Number of pages4
JournalOphthalmic Surgery Lasers and Imaging Retina
Volume46
Issue number1
DOIs
StatePublished - Jan 1 2015

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Sulfamethoxazole Drug Combination Trimethoprim
Toxoplasma
Dexamethasone
Intravitreal Injections
Optical Coherence Tomography
Therapeutics
Visual Acuity
Cicatrix
Inflammation

ASJC Scopus subject areas

  • Ophthalmology
  • Surgery

Cite this

The role of intravitreal trimethoprim/sulfamethoxazole in the treatment of toxoplasma retinochoroiditis. / Choudhury, Himadri; Jindal, Animesh; Pathengay, Avinash; Bawdekar, Abhishek; Albini, Thomas A; Flynn, Harry W.

In: Ophthalmic Surgery Lasers and Imaging Retina, Vol. 46, No. 1, 01.01.2015, p. 137-140.

Research output: Contribution to journalArticle

Choudhury, Himadri ; Jindal, Animesh ; Pathengay, Avinash ; Bawdekar, Abhishek ; Albini, Thomas A ; Flynn, Harry W. / The role of intravitreal trimethoprim/sulfamethoxazole in the treatment of toxoplasma retinochoroiditis. In: Ophthalmic Surgery Lasers and Imaging Retina. 2015 ; Vol. 46, No. 1. pp. 137-140.
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