The role of disaccharidase deficiencies in functional abdominal pain disorders—a narrative review

Mora V. Puertolas, Amanda C. Fifi

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations

Abstract

Disaccharidase deficiencies are reportedly underdiagnosed in pediatric populations. Though typically thought to cause diarrheal disease, they can also be a cause of abdominal pain and dyspepsia, and patients diagnosed with these functional disorders may actually have associated enzyme deficiencies. While the effects of lactose deficiency have been widely studied, sucrase, maltase, and isomaltase are less frequently considered when approaching a patient with an apparent functional abdominal pain disorder. This review seeks to provide an up-to-date narrative on the current scientific literature on the possible role of sucrase, maltase, and isomaltase deficiency in pediatric functional gastrointestinal disorders.

Original languageEnglish (US)
Article number1835
JournalNutrients
Volume10
Issue number12
DOIs
StatePublished - Dec 2018

Keywords

  • Functional abdominal pain
  • Functional dyspepsia
  • Irritable bowel syndrome
  • Isomaltase
  • Maltase
  • Sucrase

ASJC Scopus subject areas

  • Food Science
  • Nutrition and Dietetics

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