The role of Ca2+ as a trigger for membrane fusion.

M. Gratzl, R. Ekerdt, Gerhard Dahl

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

As revealed by freeze-fracturing, secretory vesicles isolated from pancreatic islet cells fuse when incubated with low concentration of Ca2+. The properties of this process are described and were found to be similar to those investigated with isolated secretory vesicles from different tissue origin. Secretory vesicle fusion is compared mainly with the ionic requirements of insulin secretion by the pancreatic B-cells and exocytosis by other secretory cells.

Original languageEnglish
Pages (from-to)144-149
Number of pages6
JournalHormone and Metabolic Research, Supplement
VolumeSuppl 10
StatePublished - Dec 1 1980
Externally publishedYes

Fingerprint

Membrane Fusion
Secretory Vesicles
Electric fuses
Fusion reactions
Cells
Insulin
Tissue
Membranes
Islets of Langerhans
Freeze Fracturing
Exocytosis
Insulin-Secreting Cells

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology

Cite this

The role of Ca2+ as a trigger for membrane fusion. / Gratzl, M.; Ekerdt, R.; Dahl, Gerhard.

In: Hormone and Metabolic Research, Supplement, Vol. Suppl 10, 01.12.1980, p. 144-149.

Research output: Contribution to journalArticle

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