The role of Ca2+ as a trigger for membrane fusion.

M. Gratzl; R. Ekerdt; G. Dahl

The role of Ca2+ as a trigger for membrane fusion.

M. Gratzl, R. Ekerdt, G. Dahl

Research output: Contribution to journal › Article › peer-review

Abstract

As revealed by freeze-fracturing, secretory vesicles isolated from pancreatic islet cells fuse when incubated with low concentration of Ca2+. The properties of this process are described and were found to be similar to those investigated with isolated secretory vesicles from different tissue origin. Secretory vesicle fusion is compared mainly with the ionic requirements of insulin secretion by the pancreatic B-cells and exocytosis by other secretory cells.

Original language	English (US)
Pages (from-to)	144-149
Number of pages	6
Journal	Hormone and Metabolic Research, Supplement
Volume	Suppl 10
State	Published - Dec 1 1980
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Endocrinology

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title = "The role of Ca2+ as a trigger for membrane fusion.",

abstract = "As revealed by freeze-fracturing, secretory vesicles isolated from pancreatic islet cells fuse when incubated with low concentration of Ca2+. The properties of this process are described and were found to be similar to those investigated with isolated secretory vesicles from different tissue origin. Secretory vesicle fusion is compared mainly with the ionic requirements of insulin secretion by the pancreatic B-cells and exocytosis by other secretory cells.",

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AU - Ekerdt, R.

AU - Dahl, G.

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AB - As revealed by freeze-fracturing, secretory vesicles isolated from pancreatic islet cells fuse when incubated with low concentration of Ca2+. The properties of this process are described and were found to be similar to those investigated with isolated secretory vesicles from different tissue origin. Secretory vesicle fusion is compared mainly with the ionic requirements of insulin secretion by the pancreatic B-cells and exocytosis by other secretory cells.

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