The role of amygdaloid central nucleus in the retention of differential pavlovian conditioning of bradycardia in rabbits

Christopher G. Gentile, Theodore W. Jarrell, Alan Teich, Philip M. McCabe, Neil Schneiderman

Research output: Contribution to journalArticlepeer-review

128 Scopus citations

Abstract

The present study examined the role of the amygdaloid central nucleus (ACE) in the retention of differential pavlovian conditioning of bradycardia in rabbits. Electrodes were implanted bilaterally in ACE or in control sites just dorsal and rostral to ACE. Following recovery, animals were subjected to differential pavlovian conditioning in which one tone (CS +) was paired with periorbital shock and a second tone (CS -) was presented alone. Subsequent electrolytic lesions abolished the heart rate (HR) conditioned response (CR), yet had no effect on HR orienting response, unconditioned response, or baseline. In a follow-up experiment, corneoretinal potential (CRP) and HR were recorded. Bilateral ACE lesions profoundly attenuated or abolished the HR CR without abolishing CRP CRs. The major finding of this study is that bilateral lesions of ACE selectively attenuate the HR CR while not necessarily abolishing other CRs.

Original languageEnglish (US)
Pages (from-to)263-273
Number of pages11
JournalBehavioural Brain Research
Volume20
Issue number3
DOIs
StatePublished - Jun 1986

Keywords

  • amygdaloid central nucleus
  • corneo-retinal potential
  • differential pavlovian conditioning
  • electrolytic lesion
  • heart rate
  • rabbit

ASJC Scopus subject areas

  • Behavioral Neuroscience

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