The relapse of hairy cell leukemia after a 32‐year remission

J. Donald Temple, William J. Harrington, Clyde B. McCoy

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

The optimum therapy for hairy cell leukemia (HCL) is controversial. Dramatic responses to interferon-alpha and 2'-deoxycoformycin overshadow the established role of splenectomy in HCL, and patients currently can avoid surgery altogether. A case is presented of clinical remission lasting 32 years after splenectomy-a prolonged normal life, without medication or medical intervention. When relapse occurred, the patient's response to interferon-alpha was prompt and predictable. Prognostic variables are an important consideration at the time of diagnosis in predicting the response to splenectomy.

Original languageEnglish (US)
Pages (from-to)1943-1945
Number of pages3
JournalCancer
Volume67
Issue number7
DOIs
StatePublished - Apr 1 1991

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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