Abstract
The optimum therapy for hairy cell leukemia (HCL) is controversial. Dramatic responses to interferon-alpha and 2'-deoxycoformycin overshadow the established role of splenectomy in HCL, and patients currently can avoid surgery altogether. A case is presented of clinical remission lasting 32 years after splenectomy-a prolonged normal life, without medication or medical intervention. When relapse occurred, the patient's response to interferon-alpha was prompt and predictable. Prognostic variables are an important consideration at the time of diagnosis in predicting the response to splenectomy.
Original language | English (US) |
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Pages (from-to) | 1943-1945 |
Number of pages | 3 |
Journal | Cancer |
Volume | 67 |
Issue number | 7 |
DOIs | |
State | Published - Apr 1 1991 |
ASJC Scopus subject areas
- Oncology
- Cancer Research