The regulatory effect of estrogens on fetal growth. III. Placental deoxyribonucleic acid, ribonucleic acid, and proteins

Samir N. Beydoun, Raja W. Abdul-Karim, Mary E. Haviland

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

The placental concentrations of deoxyribonucleic acid (DNA), ribonucleic acid (RNA), and total proteins were determined in control and oophorectomized-progesterone-treated (O/P) pregnant rabbits in order to elucidate the mechanism of the increase in placental weight observed in the O/P does. There was no significant difference in the placental DNA and protein concentrations between the control and experimental animals although the total placental DNA and protein contents were significantly higher in the latter. Both RNA concentration and total RNA were higher in the placentas from the oophorectomized group. These findings indicated that the increase in placental weight in the treated rabbits was caused by cellular hyperplasia, without demonstrable hypertrophy.

Original languageEnglish (US)
Pages (from-to)918-921
Number of pages4
JournalAmerican journal of obstetrics and gynecology
Volume120
Issue number7
DOIs
StatePublished - Dec 1 1974

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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