Abstract
A sensitive and specific radioimmunoassay for somatostatin (SRIF) has been used to determine the regional distribution of SRIF in rat brain. The hypothalamus contained the highest concentrations of SRIF. Lower, but significant amounts of SRIF, were present outside of the hypothelamus. Within the hypothalamus, the concentration of SRIF was highest in the median eminence and arcuate nucleus although all of the hypothalamic nuclei contained some of this material. The implications of this distribution are discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 1456-1461 |
| Number of pages | 6 |
| Journal | Endocrinology |
| Volume | 96 |
| Issue number | 6 |
| State | Published - Dec 1 1975 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Endocrinology
- Endocrinology, Diabetes and Metabolism
Cite this
The regional distribution of somatostatin in the rat brain. / Brownstein, M.; Arimura, A.; Sato, H.; Schally, Andrew V; Kizer, J. S.
In: Endocrinology, Vol. 96, No. 6, 01.12.1975, p. 1456-1461.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The regional distribution of somatostatin in the rat brain
AU - Brownstein, M.
AU - Arimura, A.
AU - Sato, H.
AU - Schally, Andrew V
AU - Kizer, J. S.
PY - 1975/12/1
Y1 - 1975/12/1
N2 - A sensitive and specific radioimmunoassay for somatostatin (SRIF) has been used to determine the regional distribution of SRIF in rat brain. The hypothalamus contained the highest concentrations of SRIF. Lower, but significant amounts of SRIF, were present outside of the hypothelamus. Within the hypothalamus, the concentration of SRIF was highest in the median eminence and arcuate nucleus although all of the hypothalamic nuclei contained some of this material. The implications of this distribution are discussed.
AB - A sensitive and specific radioimmunoassay for somatostatin (SRIF) has been used to determine the regional distribution of SRIF in rat brain. The hypothalamus contained the highest concentrations of SRIF. Lower, but significant amounts of SRIF, were present outside of the hypothelamus. Within the hypothalamus, the concentration of SRIF was highest in the median eminence and arcuate nucleus although all of the hypothalamic nuclei contained some of this material. The implications of this distribution are discussed.
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UR - http://www.scopus.com/inward/citedby.url?scp=0016705248&partnerID=8YFLogxK
M3 - Article
C2 - 1126315
AN - SCOPUS:0016705248
VL - 96
SP - 1456
EP - 1461
JO - Endocrinology
JF - Endocrinology
SN - 0013-7227
IS - 6
ER -