The regional distribution of somatostatin in the rat brain

M. Brownstein, A. Arimura, H. Sato, Andrew V Schally, J. S. Kizer

Research output: Contribution to journalArticle

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Abstract

A sensitive and specific radioimmunoassay for somatostatin (SRIF) has been used to determine the regional distribution of SRIF in rat brain. The hypothalamus contained the highest concentrations of SRIF. Lower, but significant amounts of SRIF, were present outside of the hypothelamus. Within the hypothalamus, the concentration of SRIF was highest in the median eminence and arcuate nucleus although all of the hypothalamic nuclei contained some of this material. The implications of this distribution are discussed.

Original languageEnglish
Pages (from-to)1456-1461
Number of pages6
JournalEndocrinology
Volume96
Issue number6
StatePublished - Dec 1 1975
Externally publishedYes

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Somatostatin
Radioimmunoassay
Brain
Hypothalamus
Median Eminence
Arcuate Nucleus of Hypothalamus

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Cite this

Brownstein, M., Arimura, A., Sato, H., Schally, A. V., & Kizer, J. S. (1975). The regional distribution of somatostatin in the rat brain. Endocrinology, 96(6), 1456-1461.

The regional distribution of somatostatin in the rat brain. / Brownstein, M.; Arimura, A.; Sato, H.; Schally, Andrew V; Kizer, J. S.

In: Endocrinology, Vol. 96, No. 6, 01.12.1975, p. 1456-1461.

Research output: Contribution to journalArticle

Brownstein, M, Arimura, A, Sato, H, Schally, AV & Kizer, JS 1975, 'The regional distribution of somatostatin in the rat brain', Endocrinology, vol. 96, no. 6, pp. 1456-1461.
Brownstein M, Arimura A, Sato H, Schally AV, Kizer JS. The regional distribution of somatostatin in the rat brain. Endocrinology. 1975 Dec 1;96(6):1456-1461.
Brownstein, M. ; Arimura, A. ; Sato, H. ; Schally, Andrew V ; Kizer, J. S. / The regional distribution of somatostatin in the rat brain. In: Endocrinology. 1975 ; Vol. 96, No. 6. pp. 1456-1461.
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