The pruritus receptor unit: A target for novel therapies

Gil Yosipovitch

doi:10.1038/sj.jid.5700818

The pruritus receptor unit: A target for novel therapies

Gil Yosipovitch

Research output: Contribution to journal › Comment/debate › peer-review

16 Scopus citations

Abstract

Although the role of prostanoids in itch was actively studied a decade ago, interest in this area has waned in recent years. Andoh et al. (2007, this issue) demonstrate that the prostanoid thromboxane A2 elicits scratching through its TP receptor. Identification of new itch mediators and their respective receptors within the skin will undoubtedly be the focus of future drug development for this distressing symptom.

Original language	English (US)
Pages (from-to)	1857-1859
Number of pages	3
Journal	Journal of Investigative Dermatology
Volume	127
Issue number	8
DOIs	https://doi.org/10.1038/sj.jid.5700818
State	Published - Aug 2007
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Dermatology
Cell Biology

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abstract = "Although the role of prostanoids in itch was actively studied a decade ago, interest in this area has waned in recent years. Andoh et al. (2007, this issue) demonstrate that the prostanoid thromboxane A2 elicits scratching through its TP receptor. Identification of new itch mediators and their respective receptors within the skin will undoubtedly be the focus of future drug development for this distressing symptom.",

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