The pruritus receptor unit: A target for novel therapies

Research output: Contribution to journalComment/debatepeer-review

19 Scopus citations


Although the role of prostanoids in itch was actively studied a decade ago, interest in this area has waned in recent years. Andoh et al. (2007, this issue) demonstrate that the prostanoid thromboxane A2 elicits scratching through its TP receptor. Identification of new itch mediators and their respective receptors within the skin will undoubtedly be the focus of future drug development for this distressing symptom.

Original languageEnglish (US)
Pages (from-to)1857-1859
Number of pages3
JournalJournal of Investigative Dermatology
Issue number8
StatePublished - Aug 2007
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Dermatology
  • Cell Biology


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