The pruritus receptor unit: A target for novel therapies

Gil Yosipovitch

doi:10.1038/sj.jid.5700818

The pruritus receptor unit: A target for novel therapies

Gil Yosipovitch

Research output: Contribution to journal › Comment/debate › peer-review

19 Scopus citations

Abstract

Although the role of prostanoids in itch was actively studied a decade ago, interest in this area has waned in recent years. Andoh et al. (2007, this issue) demonstrate that the prostanoid thromboxane A2 elicits scratching through its TP receptor. Identification of new itch mediators and their respective receptors within the skin will undoubtedly be the focus of future drug development for this distressing symptom.

Original language	English (US)
Pages (from-to)	1857-1859
Number of pages	3
Journal	Journal of Investigative Dermatology
Volume	127
Issue number	8
DOIs	https://doi.org/10.1038/sj.jid.5700818
State	Published - Aug 2007
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Dermatology
Cell Biology

Access to Document

10.1038/sj.jid.5700818

Cite this

@article{045b198b6f6a46609b9caa6adc532c8d,

title = "The pruritus receptor unit: A target for novel therapies",

abstract = "Although the role of prostanoids in itch was actively studied a decade ago, interest in this area has waned in recent years. Andoh et al. (2007, this issue) demonstrate that the prostanoid thromboxane A2 elicits scratching through its TP receptor. Identification of new itch mediators and their respective receptors within the skin will undoubtedly be the focus of future drug development for this distressing symptom.",

author = "Gil Yosipovitch",

year = "2007",

month = aug,

doi = "10.1038/sj.jid.5700818",

language = "English (US)",

volume = "127",

pages = "1857--1859",

journal = "Journal of Investigative Dermatology",

issn = "0022-202X",

publisher = "Nature Publishing Group",

number = "8",

}

TY - JOUR

T1 - The pruritus receptor unit

T2 - A target for novel therapies

AU - Yosipovitch, Gil

PY - 2007/8

Y1 - 2007/8

N2 - Although the role of prostanoids in itch was actively studied a decade ago, interest in this area has waned in recent years. Andoh et al. (2007, this issue) demonstrate that the prostanoid thromboxane A2 elicits scratching through its TP receptor. Identification of new itch mediators and their respective receptors within the skin will undoubtedly be the focus of future drug development for this distressing symptom.

AB - Although the role of prostanoids in itch was actively studied a decade ago, interest in this area has waned in recent years. Andoh et al. (2007, this issue) demonstrate that the prostanoid thromboxane A2 elicits scratching through its TP receptor. Identification of new itch mediators and their respective receptors within the skin will undoubtedly be the focus of future drug development for this distressing symptom.

UR - http://www.scopus.com/inward/record.url?scp=34447546641&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34447546641&partnerID=8YFLogxK

U2 - 10.1038/sj.jid.5700818

DO - 10.1038/sj.jid.5700818

M3 - Comment/debate

C2 - 17632568

AN - SCOPUS:34447546641

VL - 127

SP - 1857

EP - 1859

JO - Journal of Investigative Dermatology

JF - Journal of Investigative Dermatology

SN - 0022-202X

IS - 8

ER -

The pruritus receptor unit: A target for novel therapies

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this