Abstract
In order to estimate the prevalence of human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) co-infection in hard-to-reach intravenous drug users, 199 subjects from high-risk inner-city locales, the so called "shooting galleries", were consented, interviewed, and tested in Miami, FL, US. Positive HIV-1 status was based on repeatedly reactive ELISA and confirmatory Western Blot. Positive HCV status was based on reactive ELISA and confirmatory polymerase chain reaction techniques. Overall, 50 (25%) were not infected with either virus, 61 (31%) were HIV-1/HCV co-infected, 17 (8%) infected by HIV-1 only, and 71 (36%) infected by HCV only. The results of the multivariable analyses showed that more years using heroin was the only significant risk factor for HCV only infection (odds ratio = 1.15; 95% confidence interval = 1.07, 1.24) and for HIV-1/HCV co-infection (odds ratio = 1.17; 95% confidence interval = 1.09, 1.26). This paper demonstrates that HIV-1/HCV co-infection is highly prevalent among so called "shooting galleries".
| Original language | English |
|---|---|
| Pages (from-to) | 789-793 |
| Number of pages | 5 |
| Journal | Memorias do Instituto Oswaldo Cruz |
| Volume | 99 |
| Issue number | 8 |
| State | Published - Dec 1 2004 |
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Keywords
- Co-infection
- Hepatitis C virus
- Human immunodeficiency virus 1
- Injection drug users
ASJC Scopus subject areas
- Infectious Diseases
- Virology
- Immunology
- Microbiology (medical)
- Clinical Biochemistry
Cite this
The prevalence of human immunodeficiency virus type 1 and hepatitis C virus among injection drug users who use high risk inner-city locales in Miami, Florida. / McCoy, Clyde B; Metsch, Lisa R.; Collado-Mesa, Fernando; Arheart, Kristopher; Messiah, Sarah; Katz, Dolores; Shapshak, Paul.
In: Memorias do Instituto Oswaldo Cruz, Vol. 99, No. 8, 01.12.2004, p. 789-793.Research output: Contribution to journal › Article
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TY - JOUR
T1 - The prevalence of human immunodeficiency virus type 1 and hepatitis C virus among injection drug users who use high risk inner-city locales in Miami, Florida
AU - McCoy, Clyde B
AU - Metsch, Lisa R.
AU - Collado-Mesa, Fernando
AU - Arheart, Kristopher
AU - Messiah, Sarah
AU - Katz, Dolores
AU - Shapshak, Paul
PY - 2004/12/1
Y1 - 2004/12/1
N2 - In order to estimate the prevalence of human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) co-infection in hard-to-reach intravenous drug users, 199 subjects from high-risk inner-city locales, the so called "shooting galleries", were consented, interviewed, and tested in Miami, FL, US. Positive HIV-1 status was based on repeatedly reactive ELISA and confirmatory Western Blot. Positive HCV status was based on reactive ELISA and confirmatory polymerase chain reaction techniques. Overall, 50 (25%) were not infected with either virus, 61 (31%) were HIV-1/HCV co-infected, 17 (8%) infected by HIV-1 only, and 71 (36%) infected by HCV only. The results of the multivariable analyses showed that more years using heroin was the only significant risk factor for HCV only infection (odds ratio = 1.15; 95% confidence interval = 1.07, 1.24) and for HIV-1/HCV co-infection (odds ratio = 1.17; 95% confidence interval = 1.09, 1.26). This paper demonstrates that HIV-1/HCV co-infection is highly prevalent among so called "shooting galleries".
AB - In order to estimate the prevalence of human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) co-infection in hard-to-reach intravenous drug users, 199 subjects from high-risk inner-city locales, the so called "shooting galleries", were consented, interviewed, and tested in Miami, FL, US. Positive HIV-1 status was based on repeatedly reactive ELISA and confirmatory Western Blot. Positive HCV status was based on reactive ELISA and confirmatory polymerase chain reaction techniques. Overall, 50 (25%) were not infected with either virus, 61 (31%) were HIV-1/HCV co-infected, 17 (8%) infected by HIV-1 only, and 71 (36%) infected by HCV only. The results of the multivariable analyses showed that more years using heroin was the only significant risk factor for HCV only infection (odds ratio = 1.15; 95% confidence interval = 1.07, 1.24) and for HIV-1/HCV co-infection (odds ratio = 1.17; 95% confidence interval = 1.09, 1.26). This paper demonstrates that HIV-1/HCV co-infection is highly prevalent among so called "shooting galleries".
KW - Co-infection
KW - Hepatitis C virus
KW - Human immunodeficiency virus 1
KW - Injection drug users
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M3 - Article
C2 - 15761592
AN - SCOPUS:13844266544
VL - 99
SP - 789
EP - 793
JO - Memorias do Instituto Oswaldo Cruz
JF - Memorias do Instituto Oswaldo Cruz
SN - 0074-0276
IS - 8
ER -