The prevalence of human immunodeficiency virus type 1 and hepatitis C virus among injection drug users who use high risk inner-city locales in Miami, Florida

Clyde B. McCoy, Lisa R. Metsch, Fernando Collado-Mesa, Kristopher L. Arheart, Sarah E. Messiah, Dolores Katz, Paul Shapshak

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

In order to estimate the prevalence of human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV) co-infection in hard-to-reach intravenous drug users, 199 subjects from high-risk inner-city locales, the so called "shooting galleries", were consented, interviewed, and tested in Miami, FL, US. Positive HIV-1 status was based on repeatedly reactive ELISA and confirmatory Western Blot. Positive HCV status was based on reactive ELISA and confirmatory polymerase chain reaction techniques. Overall, 50 (25%) were not infected with either virus, 61 (31%) were HIV-1/HCV co-infected, 17 (8%) infected by HIV-1 only, and 71 (36%) infected by HCV only. The results of the multivariable analyses showed that more years using heroin was the only significant risk factor for HCV only infection (odds ratio = 1.15; 95% confidence interval = 1.07, 1.24) and for HIV-1/HCV co-infection (odds ratio = 1.17; 95% confidence interval = 1.09, 1.26). This paper demonstrates that HIV-1/HCV co-infection is highly prevalent among so called "shooting galleries".

Original languageEnglish (US)
Pages (from-to)789-793
Number of pages5
JournalMemorias do Instituto Oswaldo Cruz
Volume99
Issue number8
DOIs
StatePublished - Dec 2004

Keywords

  • Co-infection
  • Hepatitis C virus
  • Human immunodeficiency virus 1
  • Injection drug users

ASJC Scopus subject areas

  • Infectious Diseases
  • Virology
  • Immunology
  • Microbiology (medical)
  • Clinical Biochemistry

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