Abstract
HLA-B12 antigen was found in 50% and HLA-B7 was present in 49% of patients with primary open-angle glaucoma. Either one of the antigens B12 or B7 was noted in 88% of such glaucoma patients. The prevalences of B12,B7, or of either antigen were much greater in patients with primary open-angle glaucoma than in the general population or in patients with normal intraocular pressure. The prevalences in patients with ocular hypertension (lOP > 20 mm Hg) were intermediate between the ocular normotensives and the patients with primary open-angle glaucoma. The close association between HLA-B12 and HLA-B7 and primary open-angle glaucoma suggested immunologic components of the disease and possible convenient genetic markers.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 224-225 |
| Number of pages | 2 |
| Journal | Archives of ophthalmology |
| Volume | 95 |
| Issue number | 2 |
| DOIs | |
| State | Published - Feb 1977 |
| Externally published | Yes |
ASJC Scopus subject areas
- Ophthalmology
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Cite this
Shin, D. H., Becker, B., Waltman, S. R., Palmberg, P. F., & Bell, C. E. (1977). The Prevalence of HLA-B12 and HLA-B7 Antigens in Primary Open-Angle Glaucoma. Archives of ophthalmology, 95(2), 224-225. https://doi.org/10.1001/archopht.1977.04450020026003