The prevalence of fragile X in a sample of autistic individuals diagnosed using a standardized interview

J. Piven, J. Gayle, R. Landa, M. Wzorek, S. Folstein

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

The study examined 75 autistic individuals who met DSM-III-R criteria for autistic disorder at 5 years of age. Diagnosis was based on information elicited using a standardized interview for autism. Two of 75 (2.7%) autistic subjects expressed the fragile X marker (Xq27.3) in 40% of cells counted and had other affected family members. Two additional subjects expressed the fragile X anomaly at low rates (1%). These rates are compared with those reported in other studies. Methodological differences, which may underlie the varying rates reported across studies, are discussed.

Original languageEnglish
Pages (from-to)825-830
Number of pages6
JournalJournal of the American Academy of Child and Adolescent Psychiatry
Volume30
Issue number5
StatePublished - Jan 1 1991

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Autistic Disorder
Interviews
Diagnostic and Statistical Manual of Mental Disorders

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Developmental and Educational Psychology

Cite this

The prevalence of fragile X in a sample of autistic individuals diagnosed using a standardized interview. / Piven, J.; Gayle, J.; Landa, R.; Wzorek, M.; Folstein, S.

In: Journal of the American Academy of Child and Adolescent Psychiatry, Vol. 30, No. 5, 01.01.1991, p. 825-830.

Research output: Contribution to journalArticle

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