Abstract
Escherichia coli contains multiple exoribonucleases. Strains lacking the exoribonucleases RNase II, D, BN, T, and PH are inviable. The introduction of a chromosomal, wild-type copy of the gene for any one of these enzymes is sufficient to allow cell growth, with the enzymes being in the following order of effectiveness: RNase T > RNase PH > RNase D > RNase II > RNase BN. The data indicate that these five exoribonucleases functionally overlap in vivo and that any one of them can take over the functions of all the others, although with various efficiencies.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 6682-6684 |
| Number of pages | 3 |
| Journal | Journal of bacteriology |
| Volume | 174 |
| Issue number | 20 |
| DOIs |
|
| State | Published - 1992 |
ASJC Scopus subject areas
- Microbiology
- Molecular Biology
Fingerprint Dive into the research topics of 'The presence of only one of five exoribonucleases is sufficient to support the growth of Escherichia coli'. Together they form a unique fingerprint.
Cite this
Kelly, K. O., & Deutscher, M. P. (1992). The presence of only one of five exoribonucleases is sufficient to support the growth of Escherichia coli. Journal of bacteriology, 174(20), 6682-6684. https://doi.org/10.1128/jb.174.20.6682-6684.1992