TY - JOUR
T1 - The presence of only one of five exoribonucleases is sufficient to support the growth of Escherichia coli
AU - Kelly, K. O.
AU - Deutscher, M. P.
PY - 1992
Y1 - 1992
N2 - Escherichia coli contains multiple exoribonucleases. Strains lacking the exoribonucleases RNase II, D, BN, T, and PH are inviable. The introduction of a chromosomal, wild-type copy of the gene for any one of these enzymes is sufficient to allow cell growth, with the enzymes being in the following order of effectiveness: RNase T > RNase PH > RNase D > RNase II > RNase BN. The data indicate that these five exoribonucleases functionally overlap in vivo and that any one of them can take over the functions of all the others, although with various efficiencies.
AB - Escherichia coli contains multiple exoribonucleases. Strains lacking the exoribonucleases RNase II, D, BN, T, and PH are inviable. The introduction of a chromosomal, wild-type copy of the gene for any one of these enzymes is sufficient to allow cell growth, with the enzymes being in the following order of effectiveness: RNase T > RNase PH > RNase D > RNase II > RNase BN. The data indicate that these five exoribonucleases functionally overlap in vivo and that any one of them can take over the functions of all the others, although with various efficiencies.
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U2 - 10.1128/jb.174.20.6682-6684.1992
DO - 10.1128/jb.174.20.6682-6684.1992
M3 - Comment/debate
C2 - 1400219
AN - SCOPUS:0026666335
VL - 174
SP - 6682
EP - 6684
JO - Journal of Bacteriology
JF - Journal of Bacteriology
SN - 0021-9193
IS - 20
ER -