The preeminent role of childhood abuse and neglect in vulnerability to major psychiatric disorders: Toward elucidating the underlying neurobiological mechanisms

TY - JOUR

T1 - The preeminent role of childhood abuse and neglect in vulnerability to major psychiatric disorders

T2 - Toward elucidating the underlying neurobiological mechanisms

AU - Nemeroff, Charles B.

AU - Binder, Elisabeth

N1 - Funding Information: Disclosure: Dr. Nemeroff has received research/grant support from the National Institutes of Health (NIH). He has served as a consultant to Xhale, Takeda, SK Pharma, Shire, Roche, Eli Lilly and Co., Allergan, Mitsubishi Tanabe Pharma, Development America, Taisho Pharmaceutical Inc., and Lundbeck. He has held stock in CeNeRx BioPharma, PharmaNeuroBoost, Revaax Pharma, Xhale, Celgene, and Seattle Genetics. He has served on the advisory boards of American Foundation for Suicide Prevention (AFSP), CeNeRx BioPharma, National Alliance for Research on Schizophrenia and Depression (NARSAD), Xhale, PharmaNeuroBoost, Anxiety Disorders Association of America (ADAA), and Skyland Trail. He has served on the Board of Directors of AFSP, NovaDel, Skyland Trail, Gratitude America, and ADAA. He has received income sources or equity from PharmaNeuroBoost, CeNeRx BioPharma, NovaDel Pharma, Reevax Pharma, American Psychiatric Publishing, and Xhale. He holds patents in Method and devices for transdermal delivery of lithium (US 6,375,990B1) and Method of assessing antidepressant drug therapy via transport inhibition of monoamine neurotransmitters by ex vivo assay (US 7,148,027B2). He has received honoraria from the Florida Council for Community Mental Health, the Las Vegas Psychiatric Society, the World Psychiatric Association, the Saudi Psychiatric Association, the Kenes MP Asia, the American Physician Institute for Advanced Professional Studies, Asociacion de Psiquiatras de la Region de Bayamon, Florida Partners in Crisis, Global Technology Community, LLC, the International Society of Psychoneuroendocrinology, CPO Hanser Service, 1er Congreso de la Sociedad Internacional de Trastornos Bipolares, Venezuela, APA/Egyptian Psychiatric Association, YPO Partners Forum, Lieber Institute, Inc., Nevada Psychiatric Association, the University of New Mexico, World Congress of Biological Psychiatry, the University of Texas Medical Branch Galveston Grand Rounds, the Volkswagen Foundation/Herrenhausen Conference, Rush University Grand Rounds, 5th International Cardio Event 2013, CCM International Saudi Arabia/APA Meetings, CME Outfitters, CINP World Congress, the Medical University of South Carolina, Harvard Medical School/Psychopharmacology: A Master Class, the Florida Psychiatric Association, the International Society for Bipolar Disorders, 16th Annual Laura Evans Memorial Breast Cancer Symposium, Delaware State University, the University of North Carolina, New York University, NARSAD/the Brain and Behavior Research Foundation, the American Foundation for Suicide Prevention, the University of Chicago, King's College, Beth Israel Deaconess, Wright State University, the University of Texas Medical Branch, Physicians Practice Group, Augusta, GA, Londocor Event Management – South African Biological Psychiatry Congress Education SPA, Psychiatric Foundation of North Carolina, Colombian Psychiatric Association Meeting, the Anxiety and Depression Association of America, Scuola Superiore di Neuroscienze – Neuroscience School of Advanced Studies, American Psychiatric Publishing, 20th National Congress on Child Maltreatment, Bogota, Colombia, Lundbeck, Max Planck Institute, Medical Education Speaker Network, and Guarant International. He has received royalties from the American Psychiatric Association, John Wiley and Sons, Inc., The Authors Registry, Elsevier, Oxford University Press, and Cambridge University Press. He has served as an expert witness and/or legal advice consultant to Edward Health Services Corporation, Penn and Seaborn, LLC, Schochor, Federico, and Staton, PA, Great Northern Insurance Agency, Douberly and Cicero, Sotolongo, PA, and Kirby Johnson, PC. Dr. Binder reports no biomedical financial interests or potential conflicts of interest.

PY - 2014/4

Y1 - 2014/4

UR - http://www.scopus.com/inward/record.url?scp=84896484852&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84896484852&partnerID=8YFLogxK

U2 - 10.1016/j.jaac.2014.02.004

DO - 10.1016/j.jaac.2014.02.004

M3 - Editorial

C2 - 24655648

AN - SCOPUS:84896484852

VL - 53

SP - 395

EP - 397

JO - Journal of the American Academy of Child and Adolescent Psychiatry

JF - Journal of the American Academy of Child and Adolescent Psychiatry

SN - 0890-8567

IS - 4

ER -