The peripheral blood smear in patients with sickle cell trait: A morphologic observation

Christopher I. Wilson; Paulette L. Hopkins; Beria Cabello-Inchausti; Steven J. Melnick; Morton J. Robinson; Arkadi M. Rywlin

doi:10.1309/GTAK-UB4N-HPN3-GTD1

The peripheral blood smear in patients with sickle cell trait: A morphologic observation

Christopher I. Wilson, Paulette L. Hopkins, Beria Cabello-Inchausti, Steven J. Melnick, Morton J. Robinson, Arkadi M. Rywlin

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

It has been documented that individuals with sickle-cell trait (SCT) usually possess a normal complete blood cell count (CBC) and normal RBC morphology in the peripheral blood smear (PBS). We, however, have observed that the PBS of patients with SCT contains variable numbers of abnormally shaped RBCs (aRBCs), characterized by an elongated shape with tapered ends. To investigate whether these aRBCs are an invariable finding, the PBS of 71 patients with SCT and 72 patients without SCT were compared via light microscopy. Ninety-six percent of the study group had aRBCs in their PBS compared with 4% of the control group. The majority of the control group (96%) had no aRBCs (0%) in their PBS.

Original language	English (US)
Pages (from-to)	445-447
Number of pages	3
Journal	Laboratory Medicine
Volume	31
Issue number	8
DOIs	https://doi.org/10.1309/GTAK-UB4N-HPN3-GTD1
State	Published - Aug 2000
Externally published	Yes

ASJC Scopus subject areas

Clinical Biochemistry
Biochemistry, medical

Access to Document

10.1309/GTAK-UB4N-HPN3-GTD1

Cite this

@article{940764dcaf864f5aaadd193923014f2a,

title = "The peripheral blood smear in patients with sickle cell trait: A morphologic observation",

abstract = "It has been documented that individuals with sickle-cell trait (SCT) usually possess a normal complete blood cell count (CBC) and normal RBC morphology in the peripheral blood smear (PBS). We, however, have observed that the PBS of patients with SCT contains variable numbers of abnormally shaped RBCs (aRBCs), characterized by an elongated shape with tapered ends. To investigate whether these aRBCs are an invariable finding, the PBS of 71 patients with SCT and 72 patients without SCT were compared via light microscopy. Ninety-six percent of the study group had aRBCs in their PBS compared with 4% of the control group. The majority of the control group (96%) had no aRBCs (0%) in their PBS.",

author = "Wilson, {Christopher I.} and Hopkins, {Paulette L.} and Beria Cabello-Inchausti and Melnick, {Steven J.} and Robinson, {Morton J.} and Rywlin, {Arkadi M.}",

year = "2000",

month = aug,

doi = "10.1309/GTAK-UB4N-HPN3-GTD1",

language = "English (US)",

volume = "31",

pages = "445--447",

journal = "Laboratory Medicine",

issn = "0007-5027",

publisher = "American Society of Clinical Pathologists",

number = "8",

}

TY - JOUR

T1 - The peripheral blood smear in patients with sickle cell trait

T2 - A morphologic observation

AU - Wilson, Christopher I.

AU - Hopkins, Paulette L.

AU - Cabello-Inchausti, Beria

AU - Melnick, Steven J.

AU - Robinson, Morton J.

AU - Rywlin, Arkadi M.

PY - 2000/8

Y1 - 2000/8

N2 - It has been documented that individuals with sickle-cell trait (SCT) usually possess a normal complete blood cell count (CBC) and normal RBC morphology in the peripheral blood smear (PBS). We, however, have observed that the PBS of patients with SCT contains variable numbers of abnormally shaped RBCs (aRBCs), characterized by an elongated shape with tapered ends. To investigate whether these aRBCs are an invariable finding, the PBS of 71 patients with SCT and 72 patients without SCT were compared via light microscopy. Ninety-six percent of the study group had aRBCs in their PBS compared with 4% of the control group. The majority of the control group (96%) had no aRBCs (0%) in their PBS.

AB - It has been documented that individuals with sickle-cell trait (SCT) usually possess a normal complete blood cell count (CBC) and normal RBC morphology in the peripheral blood smear (PBS). We, however, have observed that the PBS of patients with SCT contains variable numbers of abnormally shaped RBCs (aRBCs), characterized by an elongated shape with tapered ends. To investigate whether these aRBCs are an invariable finding, the PBS of 71 patients with SCT and 72 patients without SCT were compared via light microscopy. Ninety-six percent of the study group had aRBCs in their PBS compared with 4% of the control group. The majority of the control group (96%) had no aRBCs (0%) in their PBS.

UR - http://www.scopus.com/inward/record.url?scp=0033862071&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033862071&partnerID=8YFLogxK

U2 - 10.1309/GTAK-UB4N-HPN3-GTD1

DO - 10.1309/GTAK-UB4N-HPN3-GTD1

M3 - Article

AN - SCOPUS:0033862071

VL - 31

SP - 445

EP - 447

JO - Laboratory Medicine

JF - Laboratory Medicine

SN - 0007-5027

IS - 8

ER -

The peripheral blood smear in patients with sickle cell trait: A morphologic observation

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this