Abstract
A fine network of corticotropin-releasing factor (CRF)-immunopositive fibers was found in the posterior lobe of the pituitary of the rat. The intermediate and distal lobes were free of CRF-immunoreactivity. Varicose, terminal-like axons were frequently observed around capillary vessels. Surgical isolation of the paraventricular nuclei resulted in a complete disappearance of CRF-immunoreactive fibers from the posterior lobe. CRF-immunopositive fibers show the general characteristics of peptidergic axons. These ultrastructural observations support the idea that CRF is secreted into capillary vessels.
| Original language | English |
|---|---|
| Pages (from-to) | 467-471 |
| Number of pages | 5 |
| Journal | Cell and Tissue Research |
| Volume | 240 |
| Issue number | 2 |
| DOIs | |
| State | Published - May 1 1985 |
| Externally published | Yes |
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Keywords
- CRF immunohistology
- Electron microscopy
- Paraventricular nuclei
- Pituitary gland, pars nervosa
- Rat
ASJC Scopus subject areas
- Anatomy
- Clinical Biochemistry
- Cell Biology
Cite this
The origin and ultrastructural characteristics of corticotropin-releasing factor (CRF)-immunoreactive nerve fibers in the posterior pituitary of the rat. / Lengvári, István; Liposits, Zsolt; Vigh, Sándor; Schally, Andrew V; Flerkó, Béla.
In: Cell and Tissue Research, Vol. 240, No. 2, 01.05.1985, p. 467-471.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The origin and ultrastructural characteristics of corticotropin-releasing factor (CRF)-immunoreactive nerve fibers in the posterior pituitary of the rat
AU - Lengvári, István
AU - Liposits, Zsolt
AU - Vigh, Sándor
AU - Schally, Andrew V
AU - Flerkó, Béla
PY - 1985/5/1
Y1 - 1985/5/1
N2 - A fine network of corticotropin-releasing factor (CRF)-immunopositive fibers was found in the posterior lobe of the pituitary of the rat. The intermediate and distal lobes were free of CRF-immunoreactivity. Varicose, terminal-like axons were frequently observed around capillary vessels. Surgical isolation of the paraventricular nuclei resulted in a complete disappearance of CRF-immunoreactive fibers from the posterior lobe. CRF-immunopositive fibers show the general characteristics of peptidergic axons. These ultrastructural observations support the idea that CRF is secreted into capillary vessels.
AB - A fine network of corticotropin-releasing factor (CRF)-immunopositive fibers was found in the posterior lobe of the pituitary of the rat. The intermediate and distal lobes were free of CRF-immunoreactivity. Varicose, terminal-like axons were frequently observed around capillary vessels. Surgical isolation of the paraventricular nuclei resulted in a complete disappearance of CRF-immunoreactive fibers from the posterior lobe. CRF-immunopositive fibers show the general characteristics of peptidergic axons. These ultrastructural observations support the idea that CRF is secreted into capillary vessels.
KW - CRF immunohistology
KW - Electron microscopy
KW - Paraventricular nuclei
KW - Pituitary gland, pars nervosa
KW - Rat
UR - http://www.scopus.com/inward/record.url?scp=0021848234&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021848234&partnerID=8YFLogxK
U2 - 10.1007/BF00222361
DO - 10.1007/BF00222361
M3 - Article
C2 - 3873278
AN - SCOPUS:0021848234
VL - 240
SP - 467
EP - 471
JO - Cell and Tissue Research
JF - Cell and Tissue Research
SN - 0302-766X
IS - 2
ER -