The Neurobiology of Anxiety Disorders: Brain Imaging, Genetics, and Psychoneuroendocrinology

Elizabeth I. Martin, Kerry J. Ressler, Elisabeth Binder, Charles B. Nemeroff

Research output: Contribution to journalReview articlepeer-review

224 Scopus citations


Anxiety disorders are highly comorbid with each other and with major depressive disorder. As syndromes, anxiety and mood disorders share many symptoms, and several treatments are effective for both. Despite this overlap, there exist many distinguishing features that support the continued classification of individual anxiety disorders that are distinct from each other and from major depression. The goal of this article is to describe the key biological similarities and differences between anxiety disorders.

Original languageEnglish (US)
Pages (from-to)549-575
Number of pages27
JournalPsychiatric Clinics of North America
Issue number3
StatePublished - Sep 2009
Externally publishedYes


  • Amygdala
  • Corticotropin-releasing factor
  • Generalized anxiety disorder
  • Panic disorder
  • Posttraumatic stress disorder
  • Social anxiety disorder

ASJC Scopus subject areas

  • Psychiatry and Mental health


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