The nephropathology in human immunodeficiency virus (HIV-1) infection

J. J. Bourgoignie, V. Pardo

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52 Scopus citations

Abstract

The nephropathology observed in patients with HIV infection is reviewed. A characteristic, though not specific, nephropathy associated with HIV infection can be encountered in HIV carriers, in patients with AIDS-related complex and in patients with AIDS. HIV-associated nephropathy typically exhibits the features of an aggressive form of focal and segmental glomerulosclerosis. Distinctive pathologic features include: 1) the "collapsing" and predominantly global pattern of glomerulosclerosis; 2) the severity of visceral epithelial cell hypertrophy and droplet formation; 3) the prominent tubular microcysts and cast formation; 4) the focal tubular degenerative features; and 5) the numerous tubuloreticular inclusions.

Original languageEnglish (US)
Pages (from-to)S-19-S-23
JournalKidney international
Volume40
Issue numberSUPPL. 35
StatePublished - 1991

ASJC Scopus subject areas

  • Nephrology

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    Bourgoignie, J. J., & Pardo, V. (1991). The nephropathology in human immunodeficiency virus (HIV-1) infection. Kidney international, 40(SUPPL. 35), S-19-S-23.