The nephropathology in human immunodeficiency virus (HIV-1) infection

Jacques J. Bourgoignie, Victoriano Pardo

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

The nephropathology observed in patients with HIV infection is reviewed. A characteristic, though not specific, nephropathy associated with HIV infection can be encountered in HIV carriers, in patients with AIDS-related complex and in patients with AIDS. HIV-associated nephropathy typically exhibits the features of an aggressive form of focal and segmental glomerulosclerosis. Distinctive pathologic features include: 1) the "collapsing" and predominantly global pattern of glomerulosclerosis; 2) the severity of visceral epithelial cell hypertrophy and droplet formation; 3) the prominent tubular microcysts and cast formation; 4) the focal tubular degenerative features; and 5) the numerous tubuloreticular inclusions.

Original languageEnglish
JournalKidney International
Volume40
Issue numberSUPPL. 35
StatePublished - Dec 1 1991

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HIV Infections
HIV-1
AIDS-Associated Nephropathy
AIDS-Related Complex
Focal Segmental Glomerulosclerosis
Hypertrophy
Acquired Immunodeficiency Syndrome
Epithelial Cells
HIV

ASJC Scopus subject areas

  • Nephrology

Cite this

The nephropathology in human immunodeficiency virus (HIV-1) infection. / Bourgoignie, Jacques J.; Pardo, Victoriano.

In: Kidney International, Vol. 40, No. SUPPL. 35, 01.12.1991.

Research output: Contribution to journalArticle

Bourgoignie, JJ & Pardo, V 1991, 'The nephropathology in human immunodeficiency virus (HIV-1) infection', Kidney International, vol. 40, no. SUPPL. 35.
Bourgoignie, Jacques J. ; Pardo, Victoriano. / The nephropathology in human immunodeficiency virus (HIV-1) infection. In: Kidney International. 1991 ; Vol. 40, No. SUPPL. 35.
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