The natural history of unruptured intracranial aneurysms.

J. Mocco; Ricardo J. Komotar; Sean D. Lavine; Philip M. Meyers; E. Sander Connolly; Robert A. Solomon

doi:10.3171/foc.2004.17.5.3

The natural history of unruptured intracranial aneurysms.

J. Mocco, Ricardo J. Komotar, Sean D. Lavine, Philip M. Meyers, E. Sander Connolly, Robert A. Solomon

Neurological Surgery

Research output: Contribution to journal › Review article › peer-review

21 Scopus citations

Abstract

Since the publication of preliminary results from the International Study of Unruptured Intracranial Aneurysms in 1998 there has been a great deal of debate concerning the natural history of these lesions and their attendant risk of aneurysmal subarachnoid hemorrhage. Therefore, the authors reviewed a selected number of crucial studies concerning this topic to determine the best evidence-based estimate of a rupture rate for these lesions. Based on this analysis, the yearly risk of bleeding for an unruptured intracranial aneurysm is estimated to be approximately 1% for aneurysms 7 to 10 mm in diameter. This risk of rupture increases with aneurysm size and it likewise diminishes as the size of the lesion decreases. This general rule serves as a reasonable interpretation of the results reported in the current body of literature.

Original language	English (US)
Pages (from-to)	E3
Journal	Neurosurgical focus
Volume	17
Issue number	5
DOIs	https://doi.org/10.3171/foc.2004.17.5.3
State	Published - Nov 15 2004

ASJC Scopus subject areas

Surgery
Clinical Neurology

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title = "The natural history of unruptured intracranial aneurysms.",

abstract = "Since the publication of preliminary results from the International Study of Unruptured Intracranial Aneurysms in 1998 there has been a great deal of debate concerning the natural history of these lesions and their attendant risk of aneurysmal subarachnoid hemorrhage. Therefore, the authors reviewed a selected number of crucial studies concerning this topic to determine the best evidence-based estimate of a rupture rate for these lesions. Based on this analysis, the yearly risk of bleeding for an unruptured intracranial aneurysm is estimated to be approximately 1% for aneurysms 7 to 10 mm in diameter. This risk of rupture increases with aneurysm size and it likewise diminishes as the size of the lesion decreases. This general rule serves as a reasonable interpretation of the results reported in the current body of literature.",

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AU - Mocco, J.

AU - Komotar, Ricardo J.

AU - Lavine, Sean D.

AU - Meyers, Philip M.

AU - Connolly, E. Sander

AU - Solomon, Robert A.

N1 - Copyright: This record is sourced from MEDLINE/PubMed, a database of the U.S. National Library of Medicine

PY - 2004/11/15

Y1 - 2004/11/15

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