The natural history of unruptured intracranial aneurysms.

J. Mocco; Ricardo J Komotar; Sean D. Lavine; Philip M. Meyers; E. Sander Connolly; Robert A. Solomon

The natural history of unruptured intracranial aneurysms.

J. Mocco, Ricardo J Komotar, Sean D. Lavine, Philip M. Meyers, E. Sander Connolly, Robert A. Solomon

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Abstract

Since the publication of preliminary results from the International Study of Unruptured Intracranial Aneurysms in 1998 there has been a great deal of debate concerning the natural history of these lesions and their attendant risk of aneurysmal subarachnoid hemorrhage. Therefore, the authors reviewed a selected number of crucial studies concerning this topic to determine the best evidence-based estimate of a rupture rate for these lesions. Based on this analysis, the yearly risk of bleeding for an unruptured intracranial aneurysm is estimated to be approximately 1% for aneurysms 7 to 10 mm in diameter. This risk of rupture increases with aneurysm size and it likewise diminishes as the size of the lesion decreases. This general rule serves as a reasonable interpretation of the results reported in the current body of literature.

Original language	English
Journal	Neurosurgical focus [electronic resource].
Volume	17
Issue number	5
State	Published - Nov 15 2004
Externally published	Yes

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Mocco, J., Komotar, R. J., Lavine, S. D., Meyers, P. M., Connolly, E. S., & Solomon, R. A. (2004). The natural history of unruptured intracranial aneurysms. Neurosurgical focus [electronic resource]., 17(5).

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T1 - The natural history of unruptured intracranial aneurysms.

AU - Mocco, J.

AU - Komotar, Ricardo J

AU - Lavine, Sean D.

AU - Meyers, Philip M.

AU - Connolly, E. Sander

AU - Solomon, Robert A.

PY - 2004/11/15

Y1 - 2004/11/15

N2 - Since the publication of preliminary results from the International Study of Unruptured Intracranial Aneurysms in 1998 there has been a great deal of debate concerning the natural history of these lesions and their attendant risk of aneurysmal subarachnoid hemorrhage. Therefore, the authors reviewed a selected number of crucial studies concerning this topic to determine the best evidence-based estimate of a rupture rate for these lesions. Based on this analysis, the yearly risk of bleeding for an unruptured intracranial aneurysm is estimated to be approximately 1% for aneurysms 7 to 10 mm in diameter. This risk of rupture increases with aneurysm size and it likewise diminishes as the size of the lesion decreases. This general rule serves as a reasonable interpretation of the results reported in the current body of literature.

AB - Since the publication of preliminary results from the International Study of Unruptured Intracranial Aneurysms in 1998 there has been a great deal of debate concerning the natural history of these lesions and their attendant risk of aneurysmal subarachnoid hemorrhage. Therefore, the authors reviewed a selected number of crucial studies concerning this topic to determine the best evidence-based estimate of a rupture rate for these lesions. Based on this analysis, the yearly risk of bleeding for an unruptured intracranial aneurysm is estimated to be approximately 1% for aneurysms 7 to 10 mm in diameter. This risk of rupture increases with aneurysm size and it likewise diminishes as the size of the lesion decreases. This general rule serves as a reasonable interpretation of the results reported in the current body of literature.

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The natural history of unruptured intracranial aneurysms.

Abstract

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