Abstract
Since the publication of preliminary results from the International Study of Unruptured Intracranial Aneurysms in 1998 there has been a great deal of debate concerning the natural history of these lesions and their attendant risk of aneurysmal subarachnoid hemorrhage. Therefore, the authors reviewed a selected number of crucial studies concerning this topic to determine the best evidence-based estimate of a rupture rate for these lesions. Based on this analysis, the yearly risk of bleeding for an unruptured intracranial aneurysm is estimated to be approximately 1% for aneurysms 7 to 10 mm in diameter. This risk of rupture increases with aneurysm size and it likewise diminishes as the size of the lesion decreases. This general rule serves as a reasonable interpretation of the results reported in the current body of literature.
| Original language | English |
|---|---|
| Journal | Neurosurgical focus [electronic resource]. |
| Volume | 17 |
| Issue number | 5 |
| State | Published - Nov 15 2004 |
| Externally published | Yes |
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The natural history of unruptured intracranial aneurysms. / Mocco, J.; Komotar, Ricardo J; Lavine, Sean D.; Meyers, Philip M.; Connolly, E. Sander; Solomon, Robert A.
In: Neurosurgical focus [electronic resource]., Vol. 17, No. 5, 15.11.2004.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The natural history of unruptured intracranial aneurysms.
AU - Mocco, J.
AU - Komotar, Ricardo J
AU - Lavine, Sean D.
AU - Meyers, Philip M.
AU - Connolly, E. Sander
AU - Solomon, Robert A.
PY - 2004/11/15
Y1 - 2004/11/15
N2 - Since the publication of preliminary results from the International Study of Unruptured Intracranial Aneurysms in 1998 there has been a great deal of debate concerning the natural history of these lesions and their attendant risk of aneurysmal subarachnoid hemorrhage. Therefore, the authors reviewed a selected number of crucial studies concerning this topic to determine the best evidence-based estimate of a rupture rate for these lesions. Based on this analysis, the yearly risk of bleeding for an unruptured intracranial aneurysm is estimated to be approximately 1% for aneurysms 7 to 10 mm in diameter. This risk of rupture increases with aneurysm size and it likewise diminishes as the size of the lesion decreases. This general rule serves as a reasonable interpretation of the results reported in the current body of literature.
AB - Since the publication of preliminary results from the International Study of Unruptured Intracranial Aneurysms in 1998 there has been a great deal of debate concerning the natural history of these lesions and their attendant risk of aneurysmal subarachnoid hemorrhage. Therefore, the authors reviewed a selected number of crucial studies concerning this topic to determine the best evidence-based estimate of a rupture rate for these lesions. Based on this analysis, the yearly risk of bleeding for an unruptured intracranial aneurysm is estimated to be approximately 1% for aneurysms 7 to 10 mm in diameter. This risk of rupture increases with aneurysm size and it likewise diminishes as the size of the lesion decreases. This general rule serves as a reasonable interpretation of the results reported in the current body of literature.
UR - http://www.scopus.com/inward/record.url?scp=33644791481&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33644791481&partnerID=8YFLogxK
M3 - Article
C2 - 15633980
AN - SCOPUS:33644791481
VL - 17
JO - Neurosurgical Focus
JF - Neurosurgical Focus
SN - 1092-0684
IS - 5
ER -