The natural history of unruptured intracranial aneurysms.

J. Mocco, Ricardo J Komotar, Sean D. Lavine, Philip M. Meyers, E. Sander Connolly, Robert A. Solomon

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Since the publication of preliminary results from the International Study of Unruptured Intracranial Aneurysms in 1998 there has been a great deal of debate concerning the natural history of these lesions and their attendant risk of aneurysmal subarachnoid hemorrhage. Therefore, the authors reviewed a selected number of crucial studies concerning this topic to determine the best evidence-based estimate of a rupture rate for these lesions. Based on this analysis, the yearly risk of bleeding for an unruptured intracranial aneurysm is estimated to be approximately 1% for aneurysms 7 to 10 mm in diameter. This risk of rupture increases with aneurysm size and it likewise diminishes as the size of the lesion decreases. This general rule serves as a reasonable interpretation of the results reported in the current body of literature.

Original languageEnglish
JournalNeurosurgical focus [electronic resource].
Volume17
Issue number5
StatePublished - Nov 15 2004
Externally publishedYes

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Intracranial Aneurysm
Natural History
Aneurysm
Rupture
Subarachnoid Hemorrhage
Publications
Hemorrhage

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Mocco, J., Komotar, R. J., Lavine, S. D., Meyers, P. M., Connolly, E. S., & Solomon, R. A. (2004). The natural history of unruptured intracranial aneurysms. Neurosurgical focus [electronic resource]., 17(5).

The natural history of unruptured intracranial aneurysms. / Mocco, J.; Komotar, Ricardo J; Lavine, Sean D.; Meyers, Philip M.; Connolly, E. Sander; Solomon, Robert A.

In: Neurosurgical focus [electronic resource]., Vol. 17, No. 5, 15.11.2004.

Research output: Contribution to journalArticle

Mocco, J, Komotar, RJ, Lavine, SD, Meyers, PM, Connolly, ES & Solomon, RA 2004, 'The natural history of unruptured intracranial aneurysms.', Neurosurgical focus [electronic resource]., vol. 17, no. 5.
Mocco J, Komotar RJ, Lavine SD, Meyers PM, Connolly ES, Solomon RA. The natural history of unruptured intracranial aneurysms. Neurosurgical focus [electronic resource]. 2004 Nov 15;17(5).
Mocco, J. ; Komotar, Ricardo J ; Lavine, Sean D. ; Meyers, Philip M. ; Connolly, E. Sander ; Solomon, Robert A. / The natural history of unruptured intracranial aneurysms. In: Neurosurgical focus [electronic resource]. 2004 ; Vol. 17, No. 5.
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