Abstract
To determine the natural history of patients with a total occlusion of a single coronary artery, we searched the Duke Databank for Cardiovascular Disease to find all patients who underwent a first coronary angiogram >2 days after a symptomatic myocardial infarction between 1969 and 1994. Patients who underwent angiography >30 days after the acute event had a low risk of death in the first year (3%), and a proximal left anterior descending coronary occlusion did not confer substantially higher risk of death (4%). Patients undergoing angiography <30 days after the acute event had a higher mortality (5%), especially those with proximal left anterior descending occlusion (10%). The time from the acute event to angiography was a predictor of death (p= 0.04). Despite low 1-year mortality rates, patients with total occlusion of an isolated coronary vessel treated medically had substantial mortality, myocardial infarction, and revascularization rates over a long-term follow- up period.
| Original language | English |
|---|---|
| Pages (from-to) | 393-399 |
| Number of pages | 7 |
| Journal | American Heart Journal |
| Volume | 133 |
| Issue number | 4 |
| State | Published - Jan 1 1997 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
The natural history of single-vessel chronic coronary occlusion : A 25- year experience. / Puma, J. A.; Sketch M.H., Jr; Tcheng, J. E.; Gardner, L. H.; Nelson, C. L.; Phillips, H. R.; Stack, R. S.; Califf, R. M.
In: American Heart Journal, Vol. 133, No. 4, 01.01.1997, p. 393-399.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The natural history of single-vessel chronic coronary occlusion
T2 - A 25- year experience
AU - Puma, J. A.
AU - Sketch M.H., Jr
AU - Tcheng, J. E.
AU - Gardner, L. H.
AU - Nelson, C. L.
AU - Phillips, H. R.
AU - Stack, R. S.
AU - Califf, R. M.
PY - 1997/1/1
Y1 - 1997/1/1
N2 - To determine the natural history of patients with a total occlusion of a single coronary artery, we searched the Duke Databank for Cardiovascular Disease to find all patients who underwent a first coronary angiogram >2 days after a symptomatic myocardial infarction between 1969 and 1994. Patients who underwent angiography >30 days after the acute event had a low risk of death in the first year (3%), and a proximal left anterior descending coronary occlusion did not confer substantially higher risk of death (4%). Patients undergoing angiography <30 days after the acute event had a higher mortality (5%), especially those with proximal left anterior descending occlusion (10%). The time from the acute event to angiography was a predictor of death (p= 0.04). Despite low 1-year mortality rates, patients with total occlusion of an isolated coronary vessel treated medically had substantial mortality, myocardial infarction, and revascularization rates over a long-term follow- up period.
AB - To determine the natural history of patients with a total occlusion of a single coronary artery, we searched the Duke Databank for Cardiovascular Disease to find all patients who underwent a first coronary angiogram >2 days after a symptomatic myocardial infarction between 1969 and 1994. Patients who underwent angiography >30 days after the acute event had a low risk of death in the first year (3%), and a proximal left anterior descending coronary occlusion did not confer substantially higher risk of death (4%). Patients undergoing angiography <30 days after the acute event had a higher mortality (5%), especially those with proximal left anterior descending occlusion (10%). The time from the acute event to angiography was a predictor of death (p= 0.04). Despite low 1-year mortality rates, patients with total occlusion of an isolated coronary vessel treated medically had substantial mortality, myocardial infarction, and revascularization rates over a long-term follow- up period.
UR - http://www.scopus.com/inward/record.url?scp=0030967470&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030967470&partnerID=8YFLogxK
M3 - Article
C2 - 9124159
AN - SCOPUS:0030967470
VL - 133
SP - 393
EP - 399
JO - American Heart Journal
JF - American Heart Journal
SN - 0002-8703
IS - 4
ER -