The natural history of intracranial carotid artery atherosclerosis.

Ricardo J. Komotar, J. Mocco, David A. Wilson, E. Sander Connolly, Sean D. Lavine, Philip M. Meyers

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


Intracranial atherosclerosis is the cause of a significant number of strokes. Despite maximal medical therapy, this disease continues to carry a poor prognosis. The authors reviewed studies in which the outcomes after conservative management in patients with intracranial carotid artery atherosclerosis were reported. Analysis of the literature demonstrates that maximal medical therapy frequently fails with this disease, leaving patients at high risk for cerebral infarction and death. A better understanding of the pathophysiological aspects and natural history of this condition may serve to guide clinical decision making and the choice of therapeutic options in this patient population.

Original languageEnglish (US)
Pages (from-to)e4
JournalNeurosurgical focus
Issue number1
StatePublished - Jan 15 2005
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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