The interface of depression and cardiovascular disease: therapeutic implications

Fred Seligman, Charles Nemeroff

Research output: Contribution to journalArticle

42 Scopus citations

Abstract

Patients with major depression are at an increased risk for developing cardiovascular disease, respond more poorly to treatment, and exhibit worse outcomes, including increased morbidity and mortality. This article reviews the relationship between depression and heart disease, with an emphasis on epidemiology, biological substrates that likely underlie this relationship, and implications for treatment.

Original languageEnglish (US)
Pages (from-to)25-35
Number of pages11
JournalAnnals of the New York Academy of Sciences
Volume1345
DOIs
StatePublished - May 1 2015

Keywords

  • antidepressants
  • cardiovascular disease
  • depression
  • mood disorders
  • platelets

ASJC Scopus subject areas

  • Medicine(all)

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