The influence of bio-behavioural factors on tumour biology: Pathways and mechanisms

Michael H. Antoni, Susan K. Lutgendorf, Steven W. Cole, Firdaus S. Dhabhar, Sandra E. Sephton, Paige Green McDonald, Michael Stefanek, Anil K. Sood

Research output: Contribution to journalReview article

630 Scopus citations

Abstract

Epidemiological studies indicate that stress, chronic depression and lack of social support might serve as risk factors for cancer development and progression. Recent cellular and molecular studies have identified biological processes that could potentially mediate such effects. This review integrates clinical, cellular and molecular studies to provide a mechanistic understanding of the interface between biological and behavioural influences in cancer, and identifies novel behavioural or pharmacological interventions that might help improve cancer outcomes.

Original languageEnglish (US)
Pages (from-to)240-248
Number of pages9
JournalNature Reviews Cancer
Volume6
Issue number3
DOIs
StatePublished - Mar 2006

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Fingerprint Dive into the research topics of 'The influence of bio-behavioural factors on tumour biology: Pathways and mechanisms'. Together they form a unique fingerprint.

  • Cite this

    Antoni, M. H., Lutgendorf, S. K., Cole, S. W., Dhabhar, F. S., Sephton, S. E., McDonald, P. G., Stefanek, M., & Sood, A. K. (2006). The influence of bio-behavioural factors on tumour biology: Pathways and mechanisms. Nature Reviews Cancer, 6(3), 240-248. https://doi.org/10.1038/nrc1820