The importance of prognostic factors in advanced prostate cancer

M. S. Soloway

Research output: Contribution to journalArticlepeer-review

48 Scopus citations


Three factors were identified in a multivariate analysis of prognostic factors in men with metastatic prostate cancer as significantly associated with their progression-free survival: 1) extent of disease on the bone scan, 2) pretreatment serum testosterone, and 3) performance status. Men with less than six bone metastases, a pretreatment testosterone > 300 ng/100 ml, and an excellent performance status will have a progression-free survival much longer than a man with more extensive bone metastases, a low testosterone prior to androgen deprivation, and a poor performance status. This information should be used to ensure proper stratification in randomized trials. It may also be helpful in identifying the patient unlikely to be helped by our current treatment. Such patient should be considered for alternative approaches with the aim of improving survival.

Original languageEnglish (US)
Pages (from-to)1017-1021
Number of pages5
Issue number5 SUPPL.
StatePublished - 1990
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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