The impact of onychomycosis on quality of life: Development of an international onychomycosis-specific questionnaire to measure patient quality of life

L. A. Drake, D. L. Patrick, P. Fleckman, J. Andre, R. Baran, E. Haneke, C. Sapede, A. Tosti

Research output: Contribution to journalArticle

132 Scopus citations

Abstract

Background: Onychomycosis is a widespread refractory disease deleteriously affecting quality of life via social stigma and disrupting daily activities. Many physicians perceive onychomycosis as a cosmetic rather than a medical problem. Objective: Our purpose was to develop a questionnaire-based instrument to quantify the impact of onychomycosis on patients' quality of life. Methods: The questionnaire was developed and validated in a multinational cross-sectional study. Completed questionnaires from 532 patients were analyzed: 284 toenail, 248 fingernail (onychomycosis or paronychia). Results: The degree of quality of life impairment from onychomycosis varied by country studied, possibly reflecting cross-national health perception differences. Longer duration of disease, greater involvement of individual nails, and greater number of nails involved were associated with more serious adverse effects. Many physicians underestimated the associated degree of pain. Conclusion: The study confirms that onychomycosis physically and psychologically affects patients' lives. The questionnaire may be a valuable tool in evaluating the effect of therapeutic agents on quality of life of patients with onychomycosis.

Original languageEnglish (US)
Pages (from-to)189-196
Number of pages8
JournalJournal of the American Academy of Dermatology
Volume41
Issue number2 I
DOIs
StatePublished - Jan 1 1999
Externally publishedYes

ASJC Scopus subject areas

  • Dermatology

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