The impact of intraoperative autologous blood transfusion during type III radical hysterectomy for early-stage cervical cancer

Ramin Mirhashemi, Hervy E. Averette, Krishnaprasad Deepika, Ricardo Estape, Roberto Angioli, Jorge Martin, Michael Rodriguez, Manuel A. Penalver

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

OBJECTIVE: The aim of this study was to determine the effects on transfusion rates, perioperative complications, and survival of using intraoperative autologous blood transfusions for patients undergoing type III radical hysterectomy and lymphadenectomy. STUDY DESIGN: A retrospective analysis was conducted on 156 patients treated with type III radical hysterectomy and lymphadenectomy at the University of Miami School of Medicine from 1990 to 1997. One group of patients (n = 50) had intraoperative autologous blood transfusions and the other (n = 106) did not. RESULTS: The group that received intraoperative autologous blood transfusion had a significant reduction in homologous blood transfusions (12% vs 30%; P= .02). Patient demographic data, histologic parameters, and operative factors were similar between the 2 groups. There was a higher percentage of patients with positive pelvic lymph nodes in the group that did not receive intraoperative autologous blood transfusion (10% vs 30%; P = .02). Seven patients in the intraoperative autologous blood transfusion group (14%) died with disease present and all the recurrences in this group were local. CONCLUSION: The use of intraoperative autologous blood transfusions during type III radical hysterectomy and lymphadenectomy appears to be safe and effective without compromising rates and patterns of recurrence.

Original languageEnglish
Pages (from-to)1310-1316
Number of pages7
JournalAmerican Journal of Obstetrics and Gynecology
Volume181
Issue number6
StatePublished - Dec 1 1999
Externally publishedYes

Fingerprint

Autologous Blood Transfusions
Hysterectomy
Uterine Cervical Neoplasms
Lymph Node Excision
Recurrence
Blood Group Antigens
Blood Transfusion
Lymph Nodes
Medicine
Demography

Keywords

  • Cell Saver
  • Cervical cancer
  • Intraoperative autologous blood transfusion
  • Radical hysterectomy

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

Cite this

Mirhashemi, R., Averette, H. E., Deepika, K., Estape, R., Angioli, R., Martin, J., ... Penalver, M. A. (1999). The impact of intraoperative autologous blood transfusion during type III radical hysterectomy for early-stage cervical cancer. American Journal of Obstetrics and Gynecology, 181(6), 1310-1316.

The impact of intraoperative autologous blood transfusion during type III radical hysterectomy for early-stage cervical cancer. / Mirhashemi, Ramin; Averette, Hervy E.; Deepika, Krishnaprasad; Estape, Ricardo; Angioli, Roberto; Martin, Jorge; Rodriguez, Michael; Penalver, Manuel A.

In: American Journal of Obstetrics and Gynecology, Vol. 181, No. 6, 01.12.1999, p. 1310-1316.

Research output: Contribution to journalArticle

Mirhashemi, R, Averette, HE, Deepika, K, Estape, R, Angioli, R, Martin, J, Rodriguez, M & Penalver, MA 1999, 'The impact of intraoperative autologous blood transfusion during type III radical hysterectomy for early-stage cervical cancer', American Journal of Obstetrics and Gynecology, vol. 181, no. 6, pp. 1310-1316.
Mirhashemi, Ramin ; Averette, Hervy E. ; Deepika, Krishnaprasad ; Estape, Ricardo ; Angioli, Roberto ; Martin, Jorge ; Rodriguez, Michael ; Penalver, Manuel A. / The impact of intraoperative autologous blood transfusion during type III radical hysterectomy for early-stage cervical cancer. In: American Journal of Obstetrics and Gynecology. 1999 ; Vol. 181, No. 6. pp. 1310-1316.
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