Abstract
The influence of diagnostic decisions and onset of illness for previously unaffected persons in a genetic linkage study are key elements in the research interface of psychiatry and molecular biology. The Amish Study has documented this process and reports its procedural methods for diagnosis of bipolar affective disorders and the impact of diagnosis on lod scores with recommendations for future family linkage study using recombinant DNA techniques.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 5-18 |
| Number of pages | 14 |
| Journal | Psychiatric Genetics |
| Volume | 1 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jan 1990 |
ASJC Scopus subject areas
- Genetics
- Genetics(clinical)
- Psychiatry and Mental health
- Biological Psychiatry
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Egeland, J. A., Sussex, J. N., Endicott, J., Hostetter, A. M., Offord, D. R., Schwab, J. J., Allen, C. R., & Pauls, D. L. (1990). The impact of diagnoses on genetic linkage study for bipolar affective disorders among the amish. Psychiatric Genetics, 1(2), 5-18. https://doi.org/10.1097/00041444-199001020-00002