The impact of diagnoses on genetic linkage study for bipolar affective disorders among the amish

Janice A. Egeland; James N. Sussex; Jean Endicott; Abram M. Hostetter; David R. Offord; John J. Schwab; Cleona R. Allen; David L. Pauls

doi:10.1097/00041444-199001020-00002

The impact of diagnoses on genetic linkage study for bipolar affective disorders among the amish

Janice A. Egeland, James N. Sussex, Jean Endicott, Abram M. Hostetter, David R. Offord, John J. Schwab, Cleona R. Allen, David L. Pauls

Psychiatry and Behavioral Sciences

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

The influence of diagnostic decisions and onset of illness for previously unaffected persons in a genetic linkage study are key elements in the research interface of psychiatry and molecular biology. The Amish Study has documented this process and reports its procedural methods for diagnosis of bipolar affective disorders and the impact of diagnosis on lod scores with recommendations for future family linkage study using recombinant DNA techniques.

Original language	English (US)
Pages (from-to)	5-18
Number of pages	14
Journal	Psychiatric Genetics
Volume	1
Issue number	2
DOIs	https://doi.org/10.1097/00041444-199001020-00002
State	Published - Jan 1990

ASJC Scopus subject areas

Genetics
Genetics(clinical)
Psychiatry and Mental health
Biological Psychiatry

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10.1097/00041444-199001020-00002

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The impact of diagnoses on genetic linkage study for bipolar affective disorders among the amish. / Egeland, Janice A.; Sussex, James N.; Endicott, Jean; Hostetter, Abram M.; Offord, David R.; Schwab, John J.; Allen, Cleona R.; Pauls, David L.

In: Psychiatric Genetics, Vol. 1, No. 2, 01.1990, p. 5-18.

Research output: Contribution to journal › Article › peer-review

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