The impact of diagnoses on genetic linkage study for bipolar affective disorders among the amish

Janice A. Egeland, James N. Sussex, Jean Endicott, Abram M. Hostetter, David R. Offord, John J. Schwab, Cleona R. Allen, David L. Pauls

Research output: Contribution to journalArticle

22 Scopus citations

Abstract

The influence of diagnostic decisions and onset of illness for previously unaffected persons in a genetic linkage study are key elements in the research interface of psychiatry and molecular biology. The Amish Study has documented this process and reports its procedural methods for diagnosis of bipolar affective disorders and the impact of diagnosis on lod scores with recommendations for future family linkage study using recombinant DNA techniques.

Original languageEnglish (US)
Pages (from-to)5-18
Number of pages14
JournalPsychiatric Genetics
Volume1
Issue number2
DOIs
StatePublished - Jan 1990

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)
  • Psychiatry and Mental health
  • Biological Psychiatry

Fingerprint Dive into the research topics of 'The impact of diagnoses on genetic linkage study for bipolar affective disorders among the amish'. Together they form a unique fingerprint.

  • Cite this

    Egeland, J. A., Sussex, J. N., Endicott, J., Hostetter, A. M., Offord, D. R., Schwab, J. J., Allen, C. R., & Pauls, D. L. (1990). The impact of diagnoses on genetic linkage study for bipolar affective disorders among the amish. Psychiatric Genetics, 1(2), 5-18. https://doi.org/10.1097/00041444-199001020-00002