The human vaccines project: A roadmap for cancer vaccine development

Pedro Romero, Jacques Banchereau, Nina Bhardwaj, Mark Cockett, Mary L. Disis, Glenn Dranoff, Eli Gilboa, Scott A. Hammond, Robert Hershberg, Alan J. Korman, Pia Kvistborg, Cornelis Melief, Ira Mellman, A. Karolina Palucka, Irina Redchenko, Harlan Robins, Federica Sallusto, Theodore Schenkelberg, Stephen Schoenberger, Jeffrey SosmanÖzlem Türeci, BenoÎt Van Den Eynde, Wayne Koff, George Couko

Research output: Contribution to journalReview article

68 Scopus citations

Abstract

Cancer vaccine development has been vigorously pursued for 40 years. Immunity to tumor antigens can be elicited bymost vaccines tested, but their clinical efficacy remainsmodest.We argue that a concerted international effort is necessary to understand the human antitumor immune response and achieve clinically effective cancer vaccines.

Original languageEnglish (US)
Article number334ps9
JournalScience Translational Medicine
Volume8
Issue number334
DOIs
StatePublished - Apr 13 2016

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Romero, P., Banchereau, J., Bhardwaj, N., Cockett, M., Disis, M. L., Dranoff, G., Gilboa, E., Hammond, S. A., Hershberg, R., Korman, A. J., Kvistborg, P., Melief, C., Mellman, I., Palucka, A. K., Redchenko, I., Robins, H., Sallusto, F., Schenkelberg, T., Schoenberger, S., ... Couko, G. (2016). The human vaccines project: A roadmap for cancer vaccine development. Science Translational Medicine, 8(334), [334ps9]. https://doi.org/10.1126/scitranslmed.aaf0685