The histological variants of liposarcoma: predictive MRI findings with prognostic implications, management, follow-up, and differential diagnosis

Magda Rizer, Adam D. Singer, Mark Edgar, Jean Jose, Ty Subhawong

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Liposarcoma is the single most common soft tissue sarcoma accounting for up to 35 % of sarcomas. It represents a histologically diverse group of soft tissue tumors that demonstrate a wide range of imaging appearances with varied behavior patterns. Correspondingly, more aggressive histological subtypes often require management that includes a combination of surgery, chemotherapy, and radiation therapy. Distinguishing among liposarcoma subtypes has important therapeutic and prognostic implications. In this manuscript, we review the liposarcoma subtypes and their histologic and MRI findings, prognostic implications, and differential diagnostic considerations.

Original languageEnglish (US)
Pages (from-to)1-12
Number of pages12
JournalSkeletal Radiology
DOIs
StateAccepted/In press - May 21 2016

Fingerprint

Liposarcoma
Differential Diagnosis
Sarcoma
Combination Drug Therapy
Radiotherapy
Neoplasms
Therapeutics

Keywords

  • Atypical lipomatous tumor
  • Follow-up
  • Liposarcoma
  • Management
  • MRI
  • Surveillance

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

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abstract = "Liposarcoma is the single most common soft tissue sarcoma accounting for up to 35 {\%} of sarcomas. It represents a histologically diverse group of soft tissue tumors that demonstrate a wide range of imaging appearances with varied behavior patterns. Correspondingly, more aggressive histological subtypes often require management that includes a combination of surgery, chemotherapy, and radiation therapy. Distinguishing among liposarcoma subtypes has important therapeutic and prognostic implications. In this manuscript, we review the liposarcoma subtypes and their histologic and MRI findings, prognostic implications, and differential diagnostic considerations.",
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T2 - predictive MRI findings with prognostic implications, management, follow-up, and differential diagnosis

AU - Rizer, Magda

AU - Singer, Adam D.

AU - Edgar, Mark

AU - Jose, Jean

AU - Subhawong, Ty

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N2 - Liposarcoma is the single most common soft tissue sarcoma accounting for up to 35 % of sarcomas. It represents a histologically diverse group of soft tissue tumors that demonstrate a wide range of imaging appearances with varied behavior patterns. Correspondingly, more aggressive histological subtypes often require management that includes a combination of surgery, chemotherapy, and radiation therapy. Distinguishing among liposarcoma subtypes has important therapeutic and prognostic implications. In this manuscript, we review the liposarcoma subtypes and their histologic and MRI findings, prognostic implications, and differential diagnostic considerations.

AB - Liposarcoma is the single most common soft tissue sarcoma accounting for up to 35 % of sarcomas. It represents a histologically diverse group of soft tissue tumors that demonstrate a wide range of imaging appearances with varied behavior patterns. Correspondingly, more aggressive histological subtypes often require management that includes a combination of surgery, chemotherapy, and radiation therapy. Distinguishing among liposarcoma subtypes has important therapeutic and prognostic implications. In this manuscript, we review the liposarcoma subtypes and their histologic and MRI findings, prognostic implications, and differential diagnostic considerations.

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KW - Management

KW - MRI

KW - Surveillance

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