The fate of homograft conduits in children with congenital heart disease: an angiographic study

Mubadda A. Salim, Thomas G. Disessa, Bruce S. Alpert, Kristopher L. Arheart, William M. Novick, Donald C. Watson

Research output: Contribution to journalArticle

22 Scopus citations

Abstract

The use of homograft conduits in the repair of congenital heart disease is widelym accept. We reviewed the catherization and angiographic data from 20 patients with ho,ograft conduits. All conduits were to the pilmonary arteries. The age at operation was 4.7 ± 5.6 years (mean ± standard deviation) and at follow-up catheterization, 7.8± 6.7 years. At implantation, conduit cross-sectional area and Z value were 219 ± 96 mm2 and 3.5 ± 1.8, respectively. At subsequent catheterization, the conduit diameters were measured in two projections at the shaft, 151 ± 92 mm2 at the annulus, 108 ± 116 mm2 at the valve opening, and 127 ± 84 mm2 at the pulmonary artery insertion. The Z values were -0.9 ± 2.5, -0.9 ± 2.8, -3.8 ± 4.0, and -2.0 ± 3.4, respectively. The crosssectional areas and the Z values at the levels of measurement were significantly smaller than the corresponding values at implantation. The change in cross-sectional areas and Z values exceeded what would be expected from growth alone. These data indicate that there is a decrease, with time, in the functional lumen of homograft conduits, and this may have implications for follow-up strategy after implantation.

Original languageEnglish (US)
Pages (from-to)67-73
Number of pages7
JournalThe Annals of Thoracic Surgery
Volume59
Issue number1
DOIs
StatePublished - Jan 1995

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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    Salim, M. A., Disessa, T. G., Alpert, B. S., Arheart, K. L., Novick, W. M., & Watson, D. C. (1995). The fate of homograft conduits in children with congenital heart disease: an angiographic study. The Annals of Thoracic Surgery, 59(1), 67-73. https://doi.org/10.1016/0003-4975(94)00674-V