The effects of volume loading on cardiorespiratory function in post-traumatic patients with adult respiratory distress syndrome

Volume loading with 250-cc aliquots of colloid divides patients into responders and nonresponders. In post-traumatic patients who do not respond to 250 cc of colloid with a return of cardiac output to normal, one should consider reducing end expiratory pressure (PEEP) and repeating the fluid challenge. In this way, the 'best' cardiovascular and pulmonary function can be obtained.