Abstract
Purpose: A prospective, double-blind study was conducted to compare the clinical efficacy of a combination of 1% tropicamide and 2.5% phenylephrine and a combination of 1% tropicamide and 10% phenylephrine for pupillary dilation in patients with diabetes. Methods: Either 2.5% phenylephrine in one eye and 10% phenylephrine in the other eye, 2.5% phenylephrine in both eyes, or 10% phenylephrine in both eyes was administered to 127 consecutive patients with diabetes. All patients received 1% tropicamide in both eyes. Results: There was no statistically significant difference in the amount of pupillary dilation between the three groups. Conclusion: As 2.5% phenylephrine may produce a lower incidence of side effects than the 10% concentration, we advise the use of the lower concentration, particularly among patients with diabetes, who already exhibit a higher prevalence of vascular disease and autonomic dysfunction.
Original language | English (US) |
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Pages (from-to) | 130-133 |
Number of pages | 4 |
Journal | Retina |
Volume | 15 |
Issue number | 2 |
DOIs | |
State | Published - Jan 1 1995 |
Keywords
- Diabetes
- Mydriasis
- Phenylephrine
- Pupillary dilation
ASJC Scopus subject areas
- Ophthalmology