The effects of albuterol and isokinetic exercise on the quadriceps muscle group

John F. Caruso, Joseph F. Signorile, Arlette C. Perry, Bill Leblanc, Richard Williams, Mike Clark, Marcas M. Bamman

Research output: Contribution to journalArticlepeer-review

91 Scopus citations


Subjects performed 9 wk of isokinetic knee extensions twice weekly. Albuterol (N = 13) or placebo (N = 9) was administered for 6 wk; groups received 16 mg · d-1 of either treatment. Training consisted of three sets of 10 repetitions at 45° · s-1. Data were collected at weeks 0, 6, and 9. Concentric and eccentric variables examined included: peak torque (CPT, EPT), total work (CTW, ETW), average power (CAP, EAP), time to peak torque (CTTPT, ETTPT), peak torque to body weight ratio (CPT/BW, EPT/BW), and work to body weight ratio (CW/BW, EW/BW). Other variables included: thigh circumference (CIRC), thigh cross-sectional area (CSA), forced vital capacity (FVC), and forced expiratory volume (FEV1). MANOVA and the Dunn-Bonferroni posthoc found differences within groups for CPT, CTW, CAP, CPT/BW, EPT, ETTPT, and CSA. Interactions were noted for CW/BW, ETW, EAP, EPT/BW, and ETW/BW; with persons administered albuterol yielding superior values. CW/BW, ETW, and EAP showed interactions at post-testing, while EPT/BW and EW/BW interacted at both midtesting and post-testing. Results indicate therapeutic doses of albuterol administered with resistance exercise may augment strength gains.

Original languageEnglish (US)
Pages (from-to)1471-1476
Number of pages6
JournalMedicine and science in sports and exercise
Issue number11
StatePublished - Nov 1995



ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Physical Therapy, Sports Therapy and Rehabilitation
  • Orthopedics and Sports Medicine


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